Results 41 to 50 of about 1,276,748 (319)

Consequences of group III/IV afferent feedback and respiratory muscle work on exercise tolerance in heart failure with reduced ejection fraction

Experimental Physiology, 2023
Exercise intolerance and exertional dyspnoea are the cardinal symptoms of heart failure with reduced ejection fraction (HFrEF). In HFrEF, abnormal autonomic and cardiopulmonary responses arising from locomotor muscle group III/IV afferent feedback is one
Joshua R. Smith, Jonathon W. Senefeld, Kathryn F. Larson, Michael J. Joyner   +3 more
doaj   +1 more source

Exercise intolerance in pulmonary arterial hypertension: insight into central and peripheral pathophysiological mechanisms

European Respiratory Review, 2021
Exercise intolerance is a cardinal symptom of pulmonary arterial hypertension (PAH) and strongly impacts patients' quality of life (QoL). Although central cardiopulmonary impairments limit peak oxygen consumption (V′O2peak) in patients with PAH, several ...
S. Malenfant, Marius Lebret, É. Breton-Gagnon, F. Potus, R. Paulin, S. Bonnet, S. Provencher   +6 more
semanticscholar   +1 more source

Moving beyond size: vorticity and energy loss are correlated with right ventricular dysfunction and exercise intolerance in repaired Tetralogy of Fallot

Journal of Cardiovascular Magnetic Resonance, 2021
Background The global effect of chronic pulmonary regurgitation (PR) on right ventricular (RV) dilation and dysfunction in repaired Tetralogy of Fallot (rTOF) patients is well studied by cardiovascular magnetic resonance (CMR). However, the links between
Y. Loke, F. Capuano, Vincent Cleveland, J. Mandell, E. Balaras, L. Olivieri   +5 more
semanticscholar   +1 more source

The H2FPEF and HFA-PEFF algorithms for predicting exercise intolerance and abnormal hemodynamics in heart failure with preserved ejection fraction

Scientific Reports, 2021
Exercise intolerance is a primary manifestation in patients with heart failure with preserved ejection fraction (HFpEF) and is associated with abnormal hemodynamics and a poor quality of life.
S. Amanai, T. Harada, K. Kagami, Kuniko Yoshida, Toshimitsu Kato, N. Wada, M. Obokata   +6 more
semanticscholar   +1 more source

Application of the speed-duration relationship to normalize the intensity of high-intensity interval training [PDF]

, 2013
The tolerable duration of continuous high-intensity exercise is determined by the hyperbolic Speed-tolerable duration (S-tLIM) relationship. However, application of the S-tLIM relationship to normalize the intensity of High-Intensity Interval Training ...
AE Tjonna, AM Jones, AM Jones, AP Turner, C Ferguson, C Ferguson, Carrie Ferguson, DC Poole, DP Swain, DP Swain, EM Coats, François Hug, G O'Donovan, HA Wenger, J Helgerud, J Myers, JC Richards, JD Bartlett, JD Bartlett, JN Morris, John Wilson, JP Little, JP Little, JP Thyfault, JR Day, JS Skinner, KA Burgomaster, KA Burgomaster, KA Burgomaster, Karen M. Birch, LJ Whyte, LJ Whyte, M Rakobowchuk, MJ Gibala, MJ Gibala, MJ Gibala, MS Hood, O Rognmo, OJ Kemi, OJ Kemi, Ole J. Kemi, PF Skiba, RH Coker, RS Paffenbarger Jr, SE Gormley, SN Blair, SR Murgatroyd, SS Bassuk, T Moholdt, T Moholdt, T Moholdt, T Moritani, U Wisloff, U Wisloff, W Chidnok, WC Knowler, WL Haskell, Z Wu   +57 more
core   +3 more sources

Dysautonomia in hypermobile Ehlers–Danlos syndrome and hypermobility spectrum disorders is associated with exercise intolerance and cardiac atrophy

medRxiv, 2021
Dysautonomia is a recognized manifestation in patients with joint hypermobility (JH) disorders. Symptoms can be highly debilitating and commonly include physical deconditioning and poor aerobic fitness.
Tania Ruiz Maya, Veronica Fettig, L. Mehta, B. Gelb, A. Kontorovich   +4 more
semanticscholar   +1 more source

Impaired myocardial relaxation with exercise determines peak aerobic exercise capacity in heart failure with preserved ejection fraction [PDF]

, 2017
Background Heart failure with preserved ejection fraction (HFpEF) is a clinical syndrome characterized by impaired exercise capacity due to shortness of breath and/or fatigue.
Abbate, Antonio, Arena, Ross, Buckley, Leo, Canada, Justin M., Carbone, Salvatore, Dixon, Dave, Trankle, Cory, Van Tassell, Benjamin   +7 more
core   +2 more sources

Imaging diagnosis-computed tomography of traction bronchiectasis secondary to pulmonary fibrosis in a Patterdale Terrier [PDF]

, 2016
An 8-year-old, Patterdale terrier was referred for evaluation of tachypnoea, exercise intolerance, and weight loss. Computed tomographic images showed pneumomediastinum, diffuse pulmonary ground glass opacity, and marked dilatation of peripheral bronchi,
Fitzgerald, E, Lamb, C R, Priestnall, S L   +2 more
core   +2 more sources

Pure exercise intolerance and ophthalmoplegia associated with the m.12,294G > A mutation in the MT-TL2 gene: a case report

BMC Musculoskeletal Disorders, 2017
Background Pure exercise intolerance associated with exclusive affection of skeletal muscle is a very rare phenotype of patients with mitochondrial myopathy.
Patrick Soldath, Karen Lindhardt Madsen, Astrid Emilie Buch, Morten Duno, Flemming Wibrand, John Vissing   +5 more
doaj   +1 more source

Locomotor and respiratory muscle abnormalities in HFrEF and HFpEF

Frontiers in Cardiovascular Medicine, 2023
Heart failure (HF) is a chronic and progressive syndrome affecting worldwide billions of patients. Exercise intolerance and early fatigue are hallmarks of HF patients either with a reduced (HFrEF) or a preserved (HFpEF) ejection fraction.
Norman Mangner, Ephraim B. Winzer, Axel Linke, Volker Adams, Volker Adams   +4 more
doaj   +1 more source