Results 41 to 50 of about 69,626 (234)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Exploring brain efficiency during exercise: A fNIRS graph theory analysis

Medicine in Novel Technology and Devices
This study seeks to elucidate the reduction in brain functional network connectivity during exercise compared to rest, utilizing graph theory techniques to analyze data from resting and movement phases across various exercise modalities.
Guangyue Zhu, Guanghu Zhang, Yichen Jiang, Wenxi Li, Dongsheng Xu   +4 more
doaj   +1 more source

Perceived exertion, postural control, and muscle recruitment in three different quadruped exercises performed by healthy women

Frontiers in Physiology, 2022
Although quadruped exercises (QE) have been a part of rehabilitation and sports programs, there is no clarity on how these exercises challenge the musculoskeletal system. Therefore, this cross-sectional study investigated the perceived exertion, postural
Patrícia Cardoso Clemente, Patrícia Cardoso Clemente, Luane Landim de Almeida, Luane Landim de Almeida, Eduardo José Danza Vicente, Diogo Simões Fonseca, Diogo Simões Fonseca, Victor Hugo Souza, Victor Hugo Souza, Victor Hugo Souza, Diogo Carvalho Felício, Marco Antonio Cavalcanti Garcia, Marco Antonio Cavalcanti Garcia, Marco Antonio Cavalcanti Garcia   +13 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Effects of stretching in a pilates program on musculoskeletal fitness: a randomized clinical trial

BMC Sports Science, Medicine and Rehabilitation
Background The scientific literature questions the impact of stretching exercises performed immediately before muscle strengthening exercises on different components of musculoskeletal physical fitness.
Alex Lopes dos Reis, Laís Campos de Oliveira, Raphael Gonçalves de Oliveira   +2 more
doaj   +1 more source

The Use of Rhythmic Auditory Stimulation to Optimize Treadmill Training for Stroke Patients: A Randomized Controlled Trial

Frontiers in Neurology, 2018
The use of functional music in gait training termed rhythmic auditory stimulation (RAS) and treadmill training (TT) have both been shown to be effective in stroke patients (SP).
Stefan Mainka, Jörg Wissel, Heinz Völler, Stefan Evers   +3 more
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

An 8-week injury prevention exercise program combined with change-of-direction technique training limits movement patterns associated with anterior cruciate ligament injury risk

Scientific Reports
Abstract Knee ligament sprains are common during change-of-direction (COD) maneuvers in multidirectional team sports. This study aimed to compare the effects of an 8-week injury prevention exercise program containing COD-specific exercises and a similar program containing linear sprint exercises on injury- and ...
Mohr, M., Federolf, P., Heinrich, D., Nitschke, M., Raschner, C., Scharbert, J., Koelewijn, A. D.   +6 more
openaire   +5 more sources