Results 61 to 70 of about 7,733,951 (272)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Postprandial lipoprotein profile in two modes of high-intensity intermittent exercise

, 2016
The aim of present study was to compare blood lipid postprandial profile response in two modes of high-intensity intermittent exercise. Twelve individuals (6 men and 6 women) were submitted to a maximal incremental test (to determine maximal aerobic ...
Lira, Fabio Santos [UNESP], Franchini, Emerson, Goncalves Panissa, Valeria Leme, Julio, Ursula Ferreira, Mello Antunes, Barbara de Moura [UNESP], Diniz, Tiego Aparecido [UNESP], Takito, Monica Yuri   +6 more
core   +1 more source

An 8-week injury prevention exercise program combined with change-of-direction technique training limits movement patterns associated with anterior cruciate ligament injury risk

Scientific Reports
Abstract Knee ligament sprains are common during change-of-direction (COD) maneuvers in multidirectional team sports. This study aimed to compare the effects of an 8-week injury prevention exercise program containing COD-specific exercises and a similar program containing linear sprint exercises on injury- and ...
Mohr, M., Federolf, P., Heinrich, D., Nitschke, M., Raschner, C., Scharbert, J., Koelewijn, A. D.   +6 more
openaire   +5 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Resistance training with slow speed of movement is better for hypertrophy and muscle strength gains than fast speed of movement. [PDF]

, 2016
Repetition speed is an important variable during resistance training. However, the effects of different speeds on the muscular strength and hypertrophy in isotonic resistance training are not clear.
Pereira, Paulo Eduardo de Assis [UNIFESP], Tanaka, Kelvin Hiroyuki [UNIFESP], Motoyama, Yuri Lopes [UNIFESP], Azevedo, Paulo Henrique Silva Marques de [UNIFESP], Botter, Luciano [UNIFESP], Esteves, Gilmar de Jesus [UNIFESP], Quinelato, William Carlos [UNIFESP]   +6 more
core  

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Resolution of electrical imaging of fluid movement in landfills

, 2011
This paper investigates the efficacy of time-lapse electrical imaging using surface electrodes to monitor the movement of leachate within a landfill. A laboratory-based study allowed direct comparison between observed physical dewatering and time-lapse ...
Barker, R.D., Jolly, J.M., Beaven, R.P.
core   +1 more source

Clinical Exercise Physiology Accreditation: An Audit of Existing Standards

, 2023
Background: Health professions such as clinical exercise physiology are founded on a set of standards that outline base level knowledge, skills, and competencies to define the roles and scope of practice of the profession.
Nathan E. Reeves, Carly Ryan, Ryan, Carly, Davison, Kade, Kade Davison, Reeves, Nathan E   +5 more
core   +1 more source

Comparative Effects of Mobilization with Movement Versus Spencer Technique Combined with Scapular Stabilization Exercises on Pain, Range of Motion, and Functional Disability in Patients with Adhesive Capsulitis

The Healer Journal of Physiotherapy and Rehabilitation Sciences
Background: Adhesive capsulitis is a painful shoulder condition causing progressive limitation of movement and functional impairment. Both mobilization with movement and the Spencer technique are commonly used in physiotherapy practice. Objective: To compare the effects of mobilization with movement and the Spencer technique, both combined with ...
Wagma Wajid, Tahir Hafeez, Siddra Yasir, Tasneem Faiz, Ejaz Ahmad, Laiba Riaz   +5 more
openaire   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source