Results 91 to 100 of about 603,898 (307)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Residual radiological opacities correlate with disease outcomes in ICU-treated COVID-19

Frontiers in Medicine
BackgroundFew studies consider both radiological and functional outcomes in COVID-19 survivors treated in the intensive care unit (ICU). We investigated clinical findings and pulmonary abnormalities on chest computed tomography (CT) and compared outcomes
Mikael Björnson, Mikael Björnson, Ann Mari Svensson, Ann Mari Svensson, Cecilia He, Magnus Sköld, Magnus Sköld, Sven Nyrén, Sven Nyrén, Malin Nygren-Bonnier, Malin Nygren-Bonnier, Judith Bruchfeld, Judith Bruchfeld, Michael Runold, Michael Runold, Francesca Campoccia Jalde, Francesca Campoccia Jalde, Anna Kistner, Anna Kistner   +18 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Detailing the mechanisms of chronic dyspnea in patients during cardiopulmonary exercise testing [PDF]

, 2021
Zafeiris Louvaris, Daniël Langer, Rik Gosselink   +2 more
openalex   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Correlation of distance walked in audio signal-modified shuttle walk test with six-minute walk test

Monaldi Archives for Chest Disease
The literature review suggested that the audio signal-modified shuttle walk test (SWTSR) was equally reliable and valid when compared to the conventional shuttle walk test.
Rishi Gopalakrishnan, Richa Hirendra Rai, Rupak Singla, Lokender Kumar, Nidhi Chandra Ponath Sivan   +4 more
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Determination of speed and assessment of conditioning in horses submitted to a lactate minimum test—alternative approaches

Frontiers in Physiology
The maximal lactate steady state (MLSS) is a well-known gold standard method for determining the aerobic capacity of athletic horses. Owing to its high cost and complex execution, there is a search for standardized exercise tests that can predict this ...
Gabriel Vieira Ramos, Angélica Cristina Titotto, Guilherme Barbosa da Costa, Guilherme de Camargo Ferraz, José Corrêa de Lacerda-Neto   +4 more
doaj   +1 more source

Assessment of functional capacity with cardiopulmonary exercise testing in non-severe COVID-19 patients at three months follow-up [PDF]

, 2020
Piero Clavario, Vincenzo De Marzo, Roberta Lotti, Cristina Bárbara, Annalisa Porcile, Carmelo Russo, Federica Beccaria, Marco Bonavia, Luigi Carlo Bottaro, Marta Caltabellotta, Flavia Chioni, Monica Santangelo, Arto J. Hautala, Pietro Ameri, Marco Canepa, Italo Porto   +15 more
openalex   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source