Exercise-Induced Desaturation During a Six-Minute Walk Test in Patients with Pulmonary Arterial Hypertension : A Retrospective, Observational Study [PDF]
Jung Hyun Choi +2 more
openalex +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Vitamin D Status and Its Relationship with Physical Function Indexes in Young Taekwondo Athletes
Background and Objective: Vitamin D increases muscle strength through protein synthesis and myogenesis and may play an important role in anaerobic and aerobic activities.
Yosef Ali Hajipour, Masoumeh Habibian
doaj
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
O teste de caminhada de 6 minutos (T6) é utilizado na avaliação de doenças cardiopulmonares por sua capacidade prognóstica, facilidade de realização e reprodutibilidade.
Elize Fumagalli +3 more
doaj
Impedance cardiography during exercise – new technology, new possibilities
Exercise impedance cardiography is a non-invasive method for the assessment of haemodynamic parameters of the cardiovascular system during exercise. Owing to the technology based on morphological analysis of the impedance signal and advanced artifact ...
Małgorzata Kurpaska +2 more
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Age Differences in Cardiopulmonary Exercise Testing Parameters in Heart Failure with Reduced Ejection Fraction [PDF]
P Garcia Bras +9 more
openalex +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source

