Results 71 to 80 of about 603,898 (307)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Exercise Training Improves Heart Rate Recovery after Exercise in Hypertension

Motriz: Revista de Educacao Fisica
Aim: This study tested the hypothesis that: 1- the exercise training would improve the heart rate recovery (HRR) decline after maximal exercise test in hypertensive patients and; 2- the exercise training would normalize HRR decline when compared to ...
Graziela Amaro-Vicente, Mateus C. Laterza, Daniel G. Martinez, Maria Janieire N. N. Alves, Ivani C. Trombetta, Ana Maria F. W. Braga, Edgar Toschi-Dias, Maria Urbana P. B. Rondon   +7 more
doaj   +1 more source

Cardiopulmonary exercise testing in young adults with surgically closed ventricular septal defects and healthy, matched control subjects: a long-term follow-up [PDF]

, 2013
Johan Heiberg, Sussie Laustsen, Petersen A. Krintel, Vibeke E. Hjortdal   +3 more
openalex   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Coronary Artery Bypass Graft Effect on Cardiogoniometry Characteristic in Patients with Coronary Heart Disease

Research in Cardiovascular Medicine
Context: Cardiogoniometry (CGM) is a noninvasive technique for quantitative three-dimensional vectorial analysis of myocardial depolarization and repolarization.
Ali Sadeghpourtabaei, Mohaddeseh Behjati, Bahador Baharestani, Fatemeh Tohidi   +3 more
doaj   +1 more source

Freqüência cardíaca máxima em testes de exercício em esteira rolante e em cicloergômetro de membros inferiores Maximal heart rate in exercise tests on treadmill and in a cycloergometer of lower limbs

Arquivos Brasileiros de Cardiologia, 2005
OBJETIVO: Comparar, retrospectivamente, os valores de freqüência cardíaca máxima (FCM) e o descenso da freqüência cardíaca no primeiro minuto da recuperação (dFC), obtidos em teste de exercício (TE) realizados em dois ergômetros e momentos distintos ...
Claudio Gil Soares de Araújo, Vivian Liane Mattos Pinto   +1 more
doaj   +1 more source

Comparing Idiopathic Chronic Fatigue and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) in Males: Response to Two-Day Cardiopulmonary Exercise Testing Protocol [PDF]

, 2021
C. M. C. van Campen, Frans C. Visser
openalex   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Comparison of distance covered, physiological cost, and perceived exertion in four six-minute walk test protocols

Frontiers in Physiology
Objective: There is evidence that indicates that the Walked Distance (WD) in the 6-Minute Walk Test (6MWT) would be sensitive to the type of track and encouragement. The aim of study was compared the impact of track type and verbal encouragement provided
Rodrigo Muñoz-Cofré, Mariano del Sol, Pablo A. Lizana, Pablo A. Lizana, Alejandro Gómez-Bruton, María José Fuentes Andaur, Erika Soto Fierro, Gabriela Osorio Gonzalez, Paul Medina-González, Fernando Valenzuela-Aedo, Máximo Escobar-Cabello   +10 more
doaj   +1 more source