Effects of metformin and exercise training, alone or in association, on cardio-pulmonary performance and quality of life in insulin resistance patients [PDF]
BACKGROUND: Metformin (MET) therapy exerts positive effects improving glucose tolerance and preventing the evolution toward diabetes in insulin resistant patients.
Bandinu, Stefano+9 more
core +1 more source
Preoperative exercise therapy for gastrointestinal cancer patients: a systematic review
BackgroundGastrointestinal cancer patients are susceptible to significant postoperative morbidity. The aim of this systematic review was to examine the effects of preoperative exercise therapy (PET) on patients undergoing surgery for GI malignancies ...
Sarah A. Vermillion+6 more
semanticscholar +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura+8 more
wiley +1 more source
Tuberculosis and the Power of the State: Toward the Development of Rational Standards for the Review of Compulsory Public Health Powers [PDF]
This article uses tuberculosis as the paradigm for exploring rational standards for the exercise of compulsory public health powers. Extant doctrine in disability and constitutional law provides a lens for examining judicial review of state interventions.
Gostin, Lawrence O.
core +2 more sources
An integrated approach in a case of facioscapulohumeral dystrophy [PDF]
BACKGROUND: Muscle fatigue, weakness and atrophy are basilar clinical features that accompany facioscapulohumeral dystrophy (FSHD) the third most common muscular dystrophy.No therapy is available for FSHD.
Berardinelli, Angela+7 more
core +1 more source
Peripheral arterial disease (PAD) is characterized by lower limb atherosclerosis impairing blood supply and causing walking-induced leg pain or claudication.
Ashley P. Akerman+5 more
semanticscholar +1 more source
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri+5 more
wiley +1 more source
The case sets the foundation for clinical protocols to incorporate mobile EEG and qEEG techniques, instrumental balance testing, and mood symptom screening in athletes who have suffered a sportsārelated concussion.
M. J. Lumb+3 more
doaj +1 more source
PENGARUH EXERCISE THERAPY JOINT MOBILITY TERHADAP TINGKAT NYERI SENDI LUTUT DAN TINGKAT MOBILITAS PADA LANSIA DI RUMAH ASUH ANAK DAN LANSIA GRIYA ASIH LAWANG [PDF]
Latar Belakang : Seiring dengan meningkatnya taraf kesehatan dan kesejahteraan, maka jumlah umat manusia yang mencapai usia lanjut semakin bertambah.
SUHARTONO, ANDRI
core
Objective To determine if exercise therapy is superior to arthroscopic partial meniscectomy for knee function in middle aged patients with degenerative meniscal tears. Design Randomised controlled superiority trial. Setting Orthopaedic departments at two
N. Kise+5 more
semanticscholar +1 more source