Results 141 to 150 of about 415,808 (314)

Alternative research strategies in the exercise - mental health relationship [PDF]

, 2005
From the numerous investigations available, there is cautious support for the proposition that exercise is associated with enhanced emotion and mood in mental illness, but the strength of the conclusions derived from the empirical findings available will
Mutrie, Nanette, Onghena, Patric, de Vliet, Peter   +2 more
core  

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Strategies to manage post-exercise glycaemia in type 1 diabetes [PDF]

For patients with type 1 diabetes, a fear of hypoglycaemia and a concern over a loss of control with wider diabetes management are the most salient barriers to exercise participation and adherence.
Campbell, Matthew
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Maximal strength training improves muscle-tendon properties and increases tendon matrix remodulation in well-trained triathletes

Scientific Reports
This study assessed the effects of a 12-week strength training (ST) intervention on Achilles and patellar tendon stiffness and tendon-matrix blood-borne markers in well-trained triathletes performing concomitant high-volume aerobic training.
Mats W. Jacobs, Joshua F. Feuerbacher, Falk Mersmann, Wilhelm Bloch, Adamantios Arampatzis, Moritz Schumann   +5 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Exercise as a prescription therapy for breast and colon cancer survivors [PDF]

, 2013
Giorgio Galanti,1 Laura Stefani,1 Gianfranco Gensini2 1Sports Medicine Center, 2Department of Medical and Surgical Critical Care, University of Florence, Florence, Italy Background: Breast and colon tumors are the most common types of cancer in the ...
Stefani L, Gensini, Gian Franco, Galanti G, Galanti, Giorgio, Gensini GF, Stefani, Laura   +5 more
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A trial of exercise therapy for women having treatment for breast cancer [PDF]

, 2010
This trial looked at the benefit of exercise therapy for women having treatment for early stage breast cancer. Doctors and breast care nurses hoped that exercise would help improve quality of life and reduce feelings of fatigue, anxiety and depression ...
Mutrie, Nanette
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