Results 71 to 80 of about 5,735,217 (364)

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

Effectiveness of Exercise Therapy and Manipulation on Sacroiliac Joint Dysfunction: A Randomized Controlled Trial.

Pain Physician, 2019
BACKGROUND The sacroiliac joint dysfunction (SIJD) has been found to be the primary culprit for lower back pain (LBP), but it is still overlooked and treated as LBP. There are no guidelines or appropriate therapeutic protocols for SIJD.
P. Nejati, Afsaneh Safarcherati, Farshid Karimi   +2 more
semanticscholar   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Effectiveness of combined therapy in physical therapy for the management of musculoskeletal pain: a systematic review and meta-analysis

Physiotherapy Quarterly
Introduction Therapeutic ultrasound and electrotherapy are commonly used in physical therapy for musculoskeletal pain (MSP) management. Combined therapy (CT) is a resource that merges both techniques, enhancing the analgesic effects of both treatments ...
Hernán Andrés de la Barra Ortiz, Cristóbal Alfaro Leiva, Camilo Alfaro Lillo, Diego Carvajal Álvarez, Bastián Cuéllar Pizarro   +4 more
doaj   +1 more source

Analysis of Cardiovascular Hemodynamic and Autonomic Variables in Individuals with Systemic Arterial Hypertension, Type 2 Diabetes Mellitus, and Parkinson’s Disease: A Comparative Study

Clinical and Experimental Hypertension, 2022
Background Systemic arterial hypertension (SAH), type 2 diabetes mellitus (T2DM), and Parkinson’s disease (PD) are highly prevalent chronic diseases that can significantly impact the cardiovascular system.
Awassi Yuphiwa Ngomane, Raphael Martins de Abreu, Bianca Fernandes, Isabela Roque Marçal, Guilherme Veiga Guimarães, Emmanuel Gomes Ciolac   +5 more
doaj   +1 more source

Exercise as Adjunct Therapy in Cancer [PDF]

Seminars in Radiation Oncology, 2019
Data from observational studies indicate that both physical activity as well as exercise (ie, structured physical activity) is associated with reductions in the risk of recurrence and cancer mortality after a diagnosis of certain forms of cancer. Emerging evidence from preclinical studies indicates that physical activity/exercise paradigms regulate ...
Kathleen A. Ashcraft, Mark W. Dewhirst, Lee W. Jones, Allison Betof Warner   +3 more
openaire   +3 more sources

Sticking to It: A Scoping Review of Adherence to Exercise Therapy Interventions in Children and Adolescents With Musculoskeletal Conditions.

Journal of Orthopaedic and Sports Physical Therapy, 2019
OBJECTIVE To identify and categorize barriers, facilitators, and strategies to boost exercise therapy adherence in youth with musculoskeletal conditions to inform research and clinical practice. DESIGN Scoping review.
C. Holt, C. Mckay, L. Truong, C. Le, D. Gross, J. L. Whittaker   +5 more
semanticscholar   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

FEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen, Zenon Toprakcioglu, Michele Vendruscolo   +2 more
wiley   +1 more source

Is there an overlooked “window of opportunity” in MS exercise therapy? Perspectives for early MS rehabilitation

Multiple Sclerosis, 2018
While early medical treatment has proven effective in MS, early-phase MS rehabilitation has not gained much attention in MS research and clinical practice. Exercise therapy is one of the most promising treatment strategies in MS rehabilitation.
Morten Riemenschneider, L. Hvid, E. Stenager, U. Dalgas   +3 more
semanticscholar   +1 more source