Results 21 to 30 of about 6,706,243 (214)

Giant hydronephrosis complicated by multiple uroepithelial carcinomas

Urology Case Reports, 2022
Giant hydronephrosis is uncommon, and malignant hydronephrosis of unknown origin is even rarer. We report a case of a 43-year-old male patient with giant hydronephrosis without painless carnivorous hematuria.
Zhen Song, Zhiyu Zhang, Zhang Chen, Bing Zhang, Jun Ouyang   +4 more
doaj   +1 more source

Diagnosis of cancer of the cervix by targeting VPAC receptors on exfoliated cervical cells

, 2023
Introduction: Cervical cancer is a major cause of cancer morbidity and mortality in women. Screening for cervical cancer reduces mortality through early detection and treatment. The success of the screening for cervical cancer has been largely attributed
Rajendra B. Nerli, Shadab Rangrez, Mahesh Kalloli, Kumar Vinchurkar, Madhukar L. Thakur, Shridhar C. Ghagane   +5 more
core   +1 more source

Senescent stromal cells promote cancer resistance through SIRT1 loss-potentiated overproduction of small extracellular vesicles [PDF]

, 2020
Cellular senescence is a potent tumor-suppressive program that prevents neoplastic events. Paradoxically, senescent cells develop an inflammatory secretome, termed the senescence-associated secretory phenotype (SASP), which is implicated in age-related ...
Jiang, Jing, Cao, Liu, Xu, Qixia, Lam, Eric W-F, Jiramongkol, Yannasittha, Han, Liu, Chin, Y Eugene, Sun, Yu, Qian, Min, Zhang, Boyi, Li, Shenjun, Guo, Jianming, Long, Qilai, Dou, Xuefeng   +13 more
core   +1 more source

Establishment and assessment of an early screening model for cervical cancer based on single-cell Raman spectroscopy combined with machine learning algorithms [PDF]

精准医学杂志
Objective To establish an early screening model for cervical cancer based on single-cell Raman spectroscopy (SCRS) combined with machine learning algorithms, and to assess the performance of the model.
MA Dongmei, ZHAO Wenjie, LIU Shihai, XU Haicang, CAI Duo, JI Yuetong, XU Jian, GUO Cancan, MA Bo, PAN Huazheng
doaj   +1 more source

Cdc42 promotes transendothelial migration of cancer cells through β1 integrin. [PDF]

, 2012
Cancer cells interact with endothelial cells during the process of metastatic spreading. Here, we use a small interfering RNA screen targeting Rho GTPases in cancer cells to identify Cdc42 as a critical regulator of cancer cell-endothelial cell ...
Valderrama, F, Riou, P, Muschel, Ruth, Susan Cox, Garg, Ritu, Vega, FM, Im, Jae Hong, Im, JH, Valderrama, Ferran, Ritu Garg, Muschel, Ruth J, Ridley, Anne J, Garg, R, Cox, Susan, Barbara Borda d’Agua, Cox, S, Vega, Francisco M., d'Agua, Barbara Borda, Reymond, N, Nicolas Reymond, Philippe Riou, Borda d'Agua, Barbara, Ferran Valderrama, Reymond, Nicolas, Jae Hong Im, Riou, Philippe, Muschel, Ruth J., Borda d'Agua, B, Ridley, AJ, Francisco M. Vega, Muschel, RJ, Anne J. Ridley, Ridley, Anne J., Vega, Francisco M, Ruth J. Muschel   +34 more
core   +1 more source

Single Cell Mechanotype and Associated Molecular Changes in Urothelial Cell Transformation and Progression

Frontiers in Cell and Developmental Biology, 2020
Cancer cell mechanotype changes are newly recognized cancer phenotypic events, whereas metastatic cancer cells show decreased cell stiffness and increased deformability relative to normal cells.
Weibo Yu, Qing-Yi Lu, Shivani Sharma, Chau Ly, Dino Di Carlo, Amy C. Rowat, Michael LeClaire, Donghyuk Kim, Christine Chow, James K. Gimzewski, Jianyu Rao   +10 more
doaj   +1 more source

HPV E6/E7, hTERT, and Ki67 mRNA RT-qPCR Assay for Detecting High-Grade Cervical Lesion with Microscope Slides

Analytical Cellular Pathology, 2019
After breast and colon cancer, cervical cancer is the third most common cancer of women worldwide. Since human papillomavirus (HPV) infection is known to be the predominant cause of cervical cancer, molecular HPV screening is currently used along with ...
Geehyuk Kim, Jemberu Taye, Kwangmin Yu, Sunyoung Park, Jungho Kim, Sunghyun Kim, Dongsup Lee, Hye-young Wang, Kwang Hwa Park, Hyeyoung Lee   +9 more
doaj   +1 more source

Determination of the differential expression of mitochondrial long non-coding RNAs as a noninvasive diagnosis of bladder cancer

BMC Urology, 2012
Background Bladder cancer is a significant cause of morbidity and mortality with a high recurrence rate. Early detection of bladder cancer is essential in order to remove the tumor, to preserve the organ and to avoid metastasis. The aim of this study was
Rivas Alexis, Burzio Verónica, Landerer Eduardo, Borgna Vincenzo, Gatica Sebastian, Ávila Rodolfo, López Constanza, Villota Claudio, de la Fuente Rodrigo, Echenique Javiera, Burzio Luis O, Villegas Jaime   +11 more
doaj   +1 more source

Preliminary study of micronuclei levels in oral exfoliated cells from patients with periodontitis

Journal of Dental Sciences, 2013
Micronuclei (MN) are abnormal nuclear structures that arise in dividing cells due to chromosomal breakage or chromosome mis-segregation, and their evaluation in oral exfoliated cells may constitute a reliable and noninvasive, cancer biomarker method ...
Diana Bastos-Aires, Álvaro Azevedo, Maria de Lurdes Pereira, Daniel Pérez-Mongiovi, Alexandra Teixeira   +4 more
doaj   +1 more source

Implantation metastasis from sigmoid colon cancer to rectal anastomosis proved by whole exome sequencing and lineage inference for cancer heterogeneity and evolution analysis: Case report and literature review

Frontiers in Oncology, 2022
It was estimated that 70% of patients with colorectal cancer were found to have viable exfoliated malignant cells in adjacent intestinal lumen. Exfoliated malignant cells had been reported to implant on raw surfaces, such as polypectomy site, anal ...
Guan Yu Yu, Guan Yu Yu, Xian Hua Gao, Xian Hua Gao, Li Jian Xia, De Bin Sun, Tao Liu, Wei Zhang, Wei Zhang   +8 more
doaj   +1 more source