Results 41 to 50 of about 6,706,243 (214)

Human Cancer Cells Express Slug-based Epithelial-Mesenchymal Transition Gene Signature Obtained in Vivo [PDF]

, 2011
The biological mechanisms underlying cancer cell motility and invasiveness remain unclear, although it has been hypothesized that they involve some type of epithelial-mesenchymal transition (EMT).
Rumjantseva Viktoria, Cheng Weiyi, Viktoria Rumjantseva, Kandel Jessica J, Jessica J Kandel, Yamashiro, Darrell, Jianzhong Huang, Peter D. Canoll, Huang, Jianzhong, Dimitris Anastassiou, Anastassiou Dimitris, Darrell J Yamashiro, Yamashiro Darrell J, Canoll Peter D, Canoll, Peter D., Kandel, Jessica J., Wei-yi Cheng, Rumjantseva, Viktoria, Huang Jianzhong, Jessica J. Kandel, Cheng, Weiyi, Darrell J. Yamashiro, Weiyi Cheng, Anastassiou, Dimitris, Peter D Canoll   +24 more
core   +2 more sources

The Value of MicroRNA-375 Detection for Triaging Primary Human Papillomavirus Positive Women: A Cross-Sectional Study in a General Population

Frontiers in Oncology, 2021
PurposeThis study aims to validate the value of microRNA (miRNA) detection for triaging human papillomavirus (HPV)-positive women in the general population.Patients and MethodsmiR-375 detection in cervical exfoliated cells has been demonstrated to have ...
Qiongyan Wu, Lingfang Wang, Xiumin Zhao, Qifang Tian, Fenfen Wang, Ni Sima, Liqian Qiu, Weiguo Lu, Xing Xie, Xinyu Wang, Xiaodong Cheng   +10 more
doaj   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Comparative Study of Genotoxicity in Different Tobacco Related Habits using Micronucleus Assay in Exfoliated Buccal Epithelial Cells [PDF]

Journal of Clinical and Diagnostic Research, 2014
Background: Oral cancer is one of the most debilitating diseases afflicting mankind. Consumption of tobacco in various forms constitutes one of the most important etiological factors in initiation of oral cancer.
Pradeep MR, Yadavalli Guruprasad, Maji Jose, Kartikay Saxena, Deepa K, Vishnudas Prabhu   +5 more
doaj   +1 more source

Observations of intracellular second-harmonic generation imaging in black phosphorus nanosheets

Journal of Innovative Optical Health Sciences, 2021
Functionalized black phosphorus (BP) nanosheets have been considered as promising nanoagents in cancer therapy due to their excellent photothermal conversion efficiency.
Xiao Peng, Yiwan Song, Zheng Peng, Kaixuan Nie, Hao Liu, Yingxin Zhou, Feifan Zhou, Yufeng Yuan, Jun Song, Junle Qu   +9 more
doaj   +1 more source

A Programmable Calcification Nanoplatform for Loco‐Regional Calcification‐Immune Hepatocellular Carcinoma Therapy

Advanced Science, EarlyView.
An in situ‐grown BP‐CaO2 nanoplatform supplies coordinated Ca2+, endogenous phosphate, and oxidative stress to convert tumor calcification from a passive endpoint into an active immune‐remodeling process. Widespread hydroxyapatite deposition is visualized by CT, while multi‐omics reveals MCOLN2 as a calcium‐responsive mediator linking biomineralization
Long Liu, Peng Li, Zhixiang Lu, Shuqin Xu, Juanjuan Wang, Kai Ma, Haodong Yu, Can Zhou, Hu Chen, Gang Liu, Yi Lyu, Shuang Bai   +11 more
wiley   +1 more source

UCtracker: A Deep Learning–Based DNA Methylation Model for Noninvasive Diagnosis and Recurrence Surveillance of Urothelial Carcinoma in a Prospective Study

Advanced Science, EarlyView.
We developed UCtracker, a urine DNA methylation–based deep learning model, for noninvasive diagnosis and postoperative surveillance of urothelial carcinoma. UCtracker demonstrates high diagnostic accuracy, robustness at ultralow sequencing depth, early recurrence detection, and dynamic risk‐stratified monitoring of molecular residual disease ...
Shengwei Xiong, Gaojie Li, Yucai Wu, Yuan Liang, Heng Guo, Yu Zhang, Gengyan Xiong, Long Tian, Xin Zhang, Ye Tian, Zhengguo Ji, Bin Guo, Yue Shi, Jian Fan, Zhihua Li, Yanqing Gong, Shiming He, Xuesong Li, Weimin Ci, Liqun Zhou   +19 more
wiley   +1 more source

Chromosomal Damage and Apoptosis in Exfoliated Buccal Cells from Individuals with Oral Cancer

International Journal of Dentistry, 2012
This study aimed to investigate cytological abnormalities indicative of chromosome damage (micronuclei) and apoptosis (karyorrhexis, pyknosis, and condensed chromatin) in exfoliated cells from the buccal mucosa of patients with oral cancer and control ...
Lavínia Tércia Magalhães Dórea, José Roberto Cardoso Meireles, Júlia Paula Ramos Lessa, Márcio Campos Oliveira, Carlos Alberto de Bragança Pereira, Adriano Polpo de Campos, Eneida de Moraes Macílio Cerqueira   +6 more
doaj   +1 more source

A comparative study for selectivity of micronuclei in oral exfoliated epithelial cells

Journal of Cytology, 2012
Background: Micronucleus (MN) represents small, additional nuclei formed by the exclusion of chromosome fragments or whole chromosomes lagging at mitosis. MN rates, therefore, indirectly reflect chromosome breakage or impairment of the mitotic apparatus.
S Grover, ABR Mujib, A Jahagirdar, N Telagi, P G Kulkarni   +4 more
doaj   +1 more source

Label-Free Morpho-Molecular Imaging for Studying the Differential Interaction of Black Phosphorus with Tumor Cells

Nanomaterials, 2022
Black phosphorus nanosheets (2D BP) are emerging as very promising, highly selective chemotherapeutic agents due to their fast degradation in the intracellular matrix of cancer cells. Here, optical diffraction tomography (ODT) and Raman spectroscopy were
Valentina Mussi, Ines Fasolino, Debadrita Paria, Sara De Simone, Maria Caporali, Manuel Serrano-Ruiz, Luigi Ambrosio, Ishan Barman, Maria Grazia Raucci, Annalisa Convertino   +9 more
doaj   +1 more source