Results 81 to 90 of about 6,706,243 (214)

Laponite Network Controls FGF‐2 Release and Drives Functional Nerve Regeneration via 3D‐Printed Nerve Wrap Interfaces

open access: yesSmall Methods, EarlyView.
We developed a 3D‐printed nerve interface integrating a biomimetic nanocomposite hydrogel with sustained delivery of thermostable FGF‐2. The bioactive interface supports Schwann cell activity and myelination while providing a regenerative microenvironment.
Diego N. Rodriguez‐Sanchez   +10 more
wiley   +1 more source

Cancer Trends: Cancer of unknown primary

open access: yes, 2019
Between 2012 and 2016, over 450 patients per year were diagnosed with a malignant cancer where the primary site of their cancer was unspecified. These cancers were identified by the presence of metastatic disease where the cancer has spread to other ...
National Cancer Registry Ireland (NCRI)
core  

The HDAC6 inhibitor C1A modulates autophagy substrates in diverse cancer cells and induces cell death [PDF]

open access: yes, 2018
BACKGROUND: Cytosolic Deacetylase HDAC6 is involved in the autophagy degradation pathway of malformed proteins, an important survival mechanism in cancer cells.
Yunqing Li   +13 more
core   +1 more source

The Potential Role of the Proteases Cathepsin D and Cathepsin L in the Progression and Metastasis of Epithelial Ovarian Cancer

open access: yesBiomolecules, 2015
Epithelial ovarian cancer (EOC) is the leading cause of death from gynecologic malignancies and has a poor prognosis due to relatively unspecific early symptoms, and thus often advanced stage, metastasized cancer at presentation. Metastasis of EOC occurs
Md Zahidul Islam Pranjol   +3 more
doaj   +1 more source

Nature‐Inspired Histidine and Guanidine Modification of Magnetic Nanoparticles for Urinary DNA Liquid Biopsy

open access: yesSmall Methods, EarlyView.
Nature‐inspired bi‐functionalized magnetic nanoparticles are engineered for the rapid, non‐invasive extraction of cell‐free DNA from unprocessed urine for liquid biopsy. These cationic particles leverage electrostatic interactions to outperform conventional kits, enhancing the recovery of short DNA fragments while maintaining DNA integrity.
Dina Haddad   +4 more
wiley   +1 more source

Cancer Trends: Cervical cancer

open access: yes, 2017
In the period 2013-2015, invasive cancer of the cervix uteri (ICD10: C53) accounted for just over 1% of all invasive cancers (excluding non-melanoma skin cancer) in Ireland, with an average of 262 cases diagnosed per year.
National Cancer Registry Ireland (NCRI)
core  

Cancer Stem Cells: Roles in Cancer Etiology

open access: yes, 2023
Cancer stem cells (CSCs) are a rare subpopulation of tumor cells with stemness properties (capable of self-renewal and differentiate into different lineages) and with increased genomic instability-bearing cells.
Islam, Farhadul
core   +1 more source

Is detection of intraperitoneal exfoliated tumor cells after surgical resection of rectal cancer a prognostic factor of survival?

open access: yesBMC Cancer, 2017
Background The prognostic significance of free cancer cells detected in peritoneal fluid at the time of rectal surgery remains unclear. A substantial number of patients will develop metastatic disease even with successful local treatment.
Christian Arstad   +4 more
doaj   +1 more source

Novel reference gene microseminoprotein‐beta based prostate cancer antigen 3 urine test: Enhanced diagnostic performance for prostate cancer and feasibility of non‐digital rectal examination urine sampling

open access: yesUroPrecision, EarlyView.
Abstract Background The diagnosis of prostate cancer (PCa) is limited by low specificity and invasiveness. This study aims to establish a highly accurate, noninvasive reverse transcription‐quantitative polymerase chain reaction (RT‐qPCR)‐based urinary prostate cancer antigen 3 (PCA3) assay system and explore the feasibility of using first‐morning urine
Jianglei Xu   +15 more
wiley   +1 more source

miR-200c sensitizes breast cancer cells to doxorubicin treatment by decreasing TrkB and Bmi1 expression. [PDF]

open access: yes, 2012
Acquired resistance to classical chemotherapeutics is a major obstacle in cancer treatment. Doxorubicin is frequently used in breast cancer therapy either as single-agent or in combination with other drugs like docetaxel and cyclophosphamide.
Oak, Prajakta S.   +11 more
core   +2 more sources

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