Results 101 to 110 of about 6,706,243 (214)

Curcumin Chemosensitizes 5-Fluorouracil Resistant MMR-Deficient Human Colon Cancer Cells in High Density Cultures [PDF]

, 2014
Objective Treatment of colorectal cancer (CRC) remains a clinical challenge, as more than 15% of patients are resistant to 5-Fluorouracil (5-FU)-based chemotherapeutic regimens, and tumor recurrence rates can be as high as 50–60%.
Patricia Kraehe, Kraehe Patricia, Shayan, Parviz, Lueders, Cora, Shayan Parviz, Lueders Cora, Shakibaei Mehdi, Mehdi Shakibaei, Parviz Shayan, Goel Ajay, Buhrmann Constanze, Ajay Goel, Cora Lueders, Shakibaei, Mehdi, Constanze Buhrmann, Buhrmann, Constanze, Goel, Ajay, Kraehe, Patricia   +17 more
core   +1 more source

Diagnosing malignant transformation potential in oral submucous fibrosis with leukoplakia: an approach utilizing deoxyribonucleic acid image cytometry

Scientific Reports
Oral submucous fibrosis (OSF) is a chronic oral condition with a potential for malignant transformation. This study aims to investigate the correlation between DNA aneuploidy and dysproliferative lesions in OSF using DNA image cytometry to provide ...
Huan Li, Wenhui Li, Liming He, Wenhui Ge, Yi Yu, Jiaming Lin, Shuangjiang Li, Xiaoyan Xie, Tianyou Ling   +8 more
doaj   +1 more source

Micronucleus Frequency Test in Epithelial Cells Desquamated From the Oral Mucosa of Patients With Fanconi Anemia

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Fanconi anemia (FA) is a rare genetic disorder predisposing patients to oral squamous cell carcinoma (OSCC). Hematopoietic stem cell transplantation (HSCT) corrects bone marrow failure but may increase the risk of malignancies. Exfoliative cytology and the micronucleus (MN) test provide noninvasive assessment of genomic instability.
Bárbara Soldatelli Ballardin, Pâmela Olivia de Moura, Pedro Leonardo Czmola de Lima, Juliana Lucena Schussel, Cassius Carvalho Torres‐Pereira   +4 more
wiley   +1 more source

GLI1 confers profound phenotypic changes upon LNCaP prostrate cancer cells that include the acquisition of a hormone independent state [PDF]

, 2011
The GLI (GLI1/GLI2) transcription factors have been implicated in the development and progression of prostate cancer although our understanding of how they actually contribute to the biology of these common tumours is limited.
Nadendla Sandeep K., Thomas, GJ, Ward, M, Lucia S. Bianchi, Hazan Allon, Ghali, Lucy, Matt Ward, Ghali Lucy, Lucia S Bianchi, Thomas, Gareth J., Michael P Philpott, Ghali, L, Philpott Michael P., Sandeep K. Nadendla, Ward Matt, Moutasim, K, Neill, GW, David M Prowse, Thomas Gareth J., Prowse, DM, Sandeep K Nadendla, Philpott, MP, Bianchi, Lucia S., Mahmoud Naase, Harper, LJ, Naase Mahmoud, Hazan, Allon, Moutasim Karwan, Philpott, Michael P., Moutasim, Karwan, Lisa J Harper, Nadendla, Sandeep K., Prowse David M., Gareth J. Thomas, Harper Lisa J., Ward, Matt, Lucy Ghali, Nadendla, SK, Allon Hazan, Hazan, A, Bianchi Lucia S., Gareth J Thomas, Graham W Neill, Karwan Moutasim, David M. Prowse, Naase, Mahmoud, Bianchi, LS, Lisa J. Harper, Prowse, David M., Harper, Lisa J., Graham W. Neill, Naase, M, Neill Graham W., Michael P. Philpott, Neill, Graham W., Bianchi, L., Ghali, L., Harper, L., Hazan, A., Thomas, G., Philpott, M., Moutasim, K., Nadenla, S., Prowse, D., Neill, G., Ward, M., Naase, M.   +66 more
core   +2 more sources

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Cell Therapy for Periodontal, Soft‐Tissue, and Craniofacial Regeneration

Journal of Periodontal Research, EarlyView.
The clinical translation of mesenchymal stem/stromal cells (MSCs) represents a major advancement in dentistry, especially for periodontal, soft‐tissue, and craniofacial regeneration. However, several challenges remain to be addressed, including the absence of standardised protocols, limited scalability, regulatory hurdles, a lack of well‐controlled ...
Kamal Mustafa, Shuntaro Yamada, Nerea Sanchez, Magdalena Mayol, Cecilie Gjerde, Mariano Sanz   +5 more
wiley   +1 more source

[Comment] Intraluminal washout in rectal and sigmoid colon cancer surgeries with double-stapling technique anastomosis: a single-institution prospective study

结直肠肛门外科
[Aim] This study aimed to determine the necessity of intraluminal washout through cytological assessment to prevent implantation of exfoliated cancer cells (ECCs) in patients with rectal and sigmoid cancers.
Huang Shenghui, Ruan Haoyang
doaj   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

Journal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed, Sara El Moshy, Israa Ahmed Radwan, Dina Rady, Aiah A. El‐Rashidy, Marwa M. S. Abbass, Christof E. Dörfer   +6 more
wiley   +1 more source

Cancer Trends: Soft Tissue Sarcomas [PDF]

, 2014
Sarcomas are a group of uncommon cancers that originate from mesenchymal cells as opposed to more well-known cancers that develop from epithelial tissue.
National Cancer Registry Ireland (NCRI)
core  

Increased Genetic Instability in Exfoliated Oral Cells in Patients With Epidermolysis Bullosa

Oral Diseases, EarlyView.
ABSTRACT Objective To analyze the nuclear abnormalities of cytotoxicity—karyorrhexis (KR), karyolysis (KL), and pyknosis (PN)—and genotoxicity—micronucleus (MN) in exfoliated cells from different sites of the oral mucosa in patients with Epidermolysis Bullosa (EB) and a control group.
Ana Carolina Sias Franco Franzosi, Rebeca Ferreira Badaró, Lucas Fernandes Leal, Rosalie Matuk Fuentes Torrelio, Willian Grassi Bautz, Leticia Nogueira da Gama‐de‐Souza   +5 more
wiley   +1 more source