Analysis of volatile organic compounds in breath as a potential diagnostic modality in disease monitoring [PDF]
The use of breath odours in medical diagnosis dates back to classical times, though in its modern form the technique is only a few decades old. There are several breath tests in common clinical use, though all of them involve administration of a known or
Patel, Mitesh Kantilal
core +7 more sources
Exhaled breath condensate biomarkers in COPD [PDF]
Biomarkers in chronic obstructive pulmonary disease may be useful in aiding diagnosis, defining specific phenotypes of disease, monitoring exacerbations and evaluating the effects of drugs. Exhaled breath condensate is a noninvasive means of sampling the airways, allowing biomarkers of airway inflammation and oxidative stress to be measured.
Borrill, Z. L., Roy, K., Singh, D.
openaire +4 more sources
Volatile diagnostic techniques for ventilator associated pneumonia [PDF]
Ventilator associated pneumonia (VAP) is a significant challenge for the Intensive Care doctors worldwide. It is both difficult to diagnose accurately and quickly and to treat effectively once the diagnosis has been established.
Humphreys, Martyn Lee
core +7 more sources
Non-Invasive Estimation of Systemic Drug Exposure Using Exhaled Breath Metabolomics in Humans: A Translational Proof-of-Concept Study. [PDF]
Accurate assessment of systemic drug exposure in humans remains challenging, as conventional approaches rely on intermittent blood sampling and laboratory‐based assays that are invasive and provide limited temporal resolution. Exhaled breath contains volatile and semi‐volatile compounds arising from drug metabolism and downstream biological processes ...
Fricke K +12 more
europepmc +2 more sources
Collecting Protein Biomarkers in Breath Using Electret Filters: A Preliminary Method on New Technical Model and Human Study. [PDF]
Biomarkers in exhaled breath are useful for respiratory disease diagnosis in human volunteers. Conventional methods that collect non-volatile biomarkers, however, necessitate an extensive dilution and sanitation processes that lowers collection ...
Wang Li +3 more
doaj +1 more source
The high sensitivity of the methods applied in breath analysis entails a high risk of detecting analytes that do not derive from endogenous production.
Michael Westhoff +2 more
doaj +1 more source
An Exhaled Breath Sampler Based on Condensational Growth and Cyclone Centrifugation (BSCC)
An exhaled breath sampler based on condensational growth and cyclone centrifugation (BSCC) was developed and evaluated. The BSCC increases the size of exhaled breath aerosols through condensational growth and then collects them as liquid sample via ...
Lebing Wang +6 more
doaj +1 more source
Cardiovascular Biomarkers in Exhaled Breath [PDF]
With each breath that we exhale, thousands of molecules are expelled in our breath, giving individuals a "breath-print" that can tell a lot about them and their state of health. Breath analysis is rapidly evolving as the new frontier in medical testing.
Frank S, Cikach, Raed A, Dweik
openaire +2 more sources
Real-Time Monitoring of Metabolism during Exercise by Exhaled Breath
Continuous monitoring of metabolites in exhaled breath has recently been introduced as an advanced method to allow non-invasive real-time monitoring of metabolite shifts during rest and acute exercise bouts.
Martin Osswald +8 more
doaj +1 more source
Effect of Food Intake on Exhaled Volatile Organic Compounds Profile Analyzed by an Electronic Nose
Exhaled breath analysis using an e-nose is a groundbreaking tool for exhaled volatile organic compound (VOC) analysis, which has already shown its applicability in several respiratory and systemic diseases.
Silvano Dragonieri +6 more
doaj +1 more source

