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The promise and perils of exhaled breath condensates
American Journal of Physiology-Lung Cellular and Molecular Physiology, 2004The exhaled breath condensate (EBC) approach provides a convenient and noninvasive approach for sampling the pulmonary epithelial lining fluid (ELF). Increased EBC concentrations of more than a dozen inflammatory markers and hydrogen ions have been reported in lung diseases associated with inflammation. However, the usefulness of EBC is compromised by
Richard M, Effros +3 more
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Exhaled breath condensate in children: Pearls and pitfalls
Pediatric Allergy and Immunology, 2004Exhaled breath condensate (EBC) is a rapidly growing field of research in respiratory medicine. Airway inflammation is a central feature of chronic lung diseases, like asthma, cystic fibrosis, bronchopulmonary dysplasia and primary ciliary dyskinesia. EBC may be a useful technique for non‐invasive assessment of markers of airway inflammation.
Rosias, P.P.R. +5 more
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Exhaled breath condensate biomarkers for lung cancer
Journal of Breath Research, 2019Abstract Lung cancer is the main cause of cancer incidence and mortality worldwide and the identification of clinically useful biomarkers for lung cancer detection at both early and metastatic stage is a pressing medical need. Although many improvements have been made in the treatment and in the early screening of this cancer, most ...
Annalisa Campanella +2 more
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Protein pattern of exhaled breath condensate and saliva
PROTEOMICS, 2002The proteins recovered in exhaled breath condensate (EBC) might be used to non-invasively monitor respiratory diseases. However, the range of proteins and their source are still unresolved and contamination by saliva or a similar protein pattern in the nasal and bronchial compartments may make interpretation of the data difficult. We studied nasal EBC (
Matthias, Griese +2 more
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Exhaled breath condensate in pulmonary arterial hypertension
Journal of Breath Research, 2012Over the last decade, several new agents have been developed for the treatment of pulmonary arterial hypertension (PAH), and blood biomarkers have been developed which aim to monitor such treatment, and which correlate well with physiological parameters, symptoms and mortality.
Geoffrey, Warwick +4 more
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Normative Data for pH of Exhaled Breath Condensate
Chest, 2006Measurement of pH is one of the simplest and most technically validated biomarkers studied in exhaled breath condensate (EBC). The pH of EBC has been found to be lower than controls in many respiratory disorders. Published data from normal control subjects have been reasonably consistent, but the data sets are not large.
Alix O, Paget-Brown +6 more
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Drinking Influences Exhaled Breath Condensate Acidity
Lung, 2008Exhaled breath condensate analysis is a developing method for investigating airway pathology. Impact of food and drink on breath condensate composition has not been systematically addressed. The aim of the study was to follow exhaled breath condensate pH after drinking an acidic and a neutral beverage.
Tamás, Kullmann +3 more
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The effect of temperature on exhaled breath condensate collection
Journal of Breath Research, 2012Exhaled breath condensate (EBC) collection is an innovative method of non-invasively sampling the lung, and can detect a variety of volatile and non-volatile biomarkers, but the disadvantage is the small volume of sample collected. It was hypothesized that a collection system at a lower temperature would increase the volume collected, but may alter the
Aditya, Vyas +7 more
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Metabolomics in Exhaled Breath Condensates
American Journal of Respiratory and Critical Care Medicine, 2008CARRARO, SILVIA +4 more
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