Results 131 to 140 of about 937,952 (246)

Updates in COPD Management: From Inflammatory Pathways to Targeted Therapies

European Journal of Clinical Investigation, Volume 56, Issue 10, October 2026.
COPD is a heterogeneous disease driven by overlapping neutrophilic and eosinophilic inflammatory pathways. This review highlights the shift from symptom‐based treatment toward phenotype‐ and biomarker‐directed care. Blood eosinophils, FeNO, and IgE predict corticosteroid responsiveness and identify candidates for biologic therapy.
Sasha Raman, Sreya Rahman, Francesca Polverino, Muhammad Adrish   +3 more
wiley   +1 more source

Early predictors of persistent childhood asthma and allergic rhinitis: A machine learning study using post‐hoc explainability

Pediatric Allergy and Immunology, Volume 37, Issue 10, October 2026.
Machine learning models applied to detailed early‐life data showed limited ability to predict which children developed persistent asthma or allergic rhinitis. Although clinically plausible features contributed to predictions, model performance was insufficient for reliable individual prognostic stratification.
Frederikke Rosenvinge Skov, Mario Lovrić, Tamo Sultan, Klaus Bønnelykke, Bo Chawes, Jakob Stokholm, Jonathan Thorsen, Morten Arendt Rasmussen, Ann‐Marie Malby Schoos   +8 more
wiley   +1 more source

Effect of an acute exercise bout on alveolar–capillary membrane permeability and interstitial fluid accumulation in COPD

Experimental Physiology, Volume 111, Issue 10, Page 4315-4327, 1 October 2026.
Abstract Exertional dyspnoea is a debilitating symptom in chronic obstructive pulmonary disease (COPD) and often persists after the cessation of exercise. The underlying mechanisms are not fully understood, and a potential contributing factor that has not previously been investigated is alveolar–capillary membrane breaching with extravasation of fluid ...
Rie Skovly Thomsen, Iben Elmerdahl Rasmussen, Stine Buus Nymand, Anna Agnes Lytzen, Jacob Peter Hartmann, Milan Mohammad, Malte Lund Adamsen, Birgitte Hanel, Jann Mortensen, Ronan M. G. Berg   +9 more
wiley   +1 more source

Curcumin improves endothelial dysfunction and vascular remodeling in 2K-1C hypertensive rats by raising nitric oxide availability and reducing oxidative stress [PDF]

, 2014
Pakdeechote, P, Boonla, O, Pannangpetch, P, Kukongviriyapan, V, Kukongviriyapan, U, Greenwald, SE, Prachaney, P   +6 more
core   +1 more source

Importance of fractional exhaled nitric oxide in the differentiation of asthma–COPD overlap syndrome, asthma, and COPD

, 2016
Feng-jia Chen,* Xin-yan Huang,* Yang-li Liu, Geng-peng Lin, Can-mao Xie Department of Respiratory Disease, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, People’s Republic of China *These authors contributed equally to this ...
Lin GP, Huang XY, Liu YL, Xie CM, Chen FJ   +4 more
core  

Nitric Oxide (NO)

, 2015
Nitric oxide plays a significant role in atmospheric phenomena and pollution. It helps to create ozone in the lower atmosphere where it is not needed, and again unfortunately helps to remove ozone from the higher levels of the atmosphere where it is ...
MARINAKIS, S, Howard,, B
core   +1 more source

Exhaled nitric oxide in diagnosis and management of respiratory diseases

Annals of Thoracic Medicine, 2009
The analysis of biomarkers in exhaled breath constituents has recently become of great interest in the diagnosis, treatment and monitoring of many respiratory conditions. Of particular interest is the measurement of fractional exhaled nitric oxide (FENO)
Abba Abdullah
doaj  

Two-year outcomes of a randomized controlled trial of inhaled nitric oxide in premature infants

, 2013
: BACKGROUND AND OBJECTIVES: The European Union Nitric Oxide trial was designed to assess the potential benefits of inhaled nitric oxide (iNO) compared with placebo in infants with respiratory failure.
Hummler, Helmut, Sanchez-Luna, Manuel, Durrmeyer, Xavier, van Overmeire, Bart, et al.   +4 more
core  

Cost-effectiveness of fractional exhaled nitric oxide (FeNO) measurement in predicting response to omalizumab in asthma

, 2019
Elizabeth A Brooks,1 Marc Massanari,2 Nicola A Hanania,3 Daniel J Weiner11TTi Health Research & Economics, Health Research & Economics, Westminster, MD, USA; 2Circassia Pharmaceuticals, Global Medical Affairs, Morrisville, NC, USA; 3Section of ...
Brooks EA, Massanari M, Hanania NA, Weiner DJ   +3 more
core  

Estimating nasal nitric oxide from measured fractional exhaled nitric oxide and nasal fractional exhaled nitric oxide. [PDF]

J Thorac Dis
Abo M, Tsumaya Y, Ohki T, Takeda Y, Kobayashi T, Ueno T, Matsuda Y, Nakade Y, Yamamura K, Watanabe S, Ohkura N, Hara J, Yano S, Gon Y.   +13 more
europepmc   +1 more source