Results 31 to 40 of about 13,960 (212)

Caffeine decreases exhaled nitric oxide [PDF]

Thorax, 2002
Caffeine is known to inhibit phosphodiesterases, to mobilise intracellular calcium, and to act as an antagonist at adenosine receptors, all of which can potentially alter nitric oxide (NO) production. It was therefore hypothesised that caffeine may alter exhaled NO (eNO) levels.In a randomised, single blind, crossover manner, 12 normal subjects ...
C, Bruce, D H, Yates, P S, Thomas
openaire   +2 more sources

Factors attributable to the level of exhaled nitric oxide in asthmatic children

European Journal of Medical Research, 2009
Background Asthma is a heterogeneous disease with variable symptoms especially in children. Exhaled nitric oxide (FeNO) has proved to be a marker of inflammation in the airways and has become a substantial part of clinical management of asthmatic ...
Banovcin P, Jesenak M, Michnova Z, Babusikova E, Nosal S, Mikler J, Fabry J, Barreto M   +7 more
doaj   +1 more source

Effect of Inhaled β2-Agonist on Exhaled Nitric Oxide in Chronic Obstructive Pulmonary Disease. [PDF]

PLoS ONE, 2016
The fractional exhaled nitric oxide measured at an expiratory flow of 50mL/s (FENO50) is a marker of airway inflammation, and high levels are associated with greater response to steroid treatment.
Mostafa Amer, Jan Cowan, Andrew Gray, Ben Brockway, Jack Dummer, Jack Dummer   +5 more
doaj   +1 more source

Pharmacokinetics and safety of tezepelumab in children with mild, moderate or severe asthma and adolescents with mild‐to‐moderate asthma

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tezepelumab is a human monoclonal antibody that blocks the activity of thymic stromal lymphopoietin and is approved for adolescents and adults with severe asthma. This analysis assessed pharmacokinetics (PK), pharmacodynamics and safety of tezepelumab up to 85 days postdose in adolescents and children.
Anna Lundahl, Jonathan Grigg, Lubna Abuqayyas, Piotr Kuna, Gillian Hunter, Beata Pawlikowska, Jacob Leander, Michael Levin, Atul Gupta, James Paton, Katharine C. Pike, Jane R. Parnes, Gun Almqvist, Stephanie L. Roseti, on behalf of the study investigators   +14 more
wiley   +1 more source

Exhaled Nitric Oxide and Pulmonary Oxygen Toxicity Susceptibility

Metabolites, 2023
Individual susceptibility to pulmonary oxygen toxicity (PO2tox) is highly variable and currently lacks a reliable biomarker for predicting pulmonary hyperoxic stress. As nitric oxide (NO) is involved in many respiratory system processes and functions, we
David M. Fothergill, Jeffery W. Gertner
doaj   +1 more source

Inflammatory Factors in Allergic Rhinitis: A 20‐Year Bibliometric Mapping and Emerging Trends

Flavour and Fragrance Journal, EarlyView.
This figure illustrates the bibliometric process and results of research on inflammatory factors of allergic rhinitis from 2004 to 2024 including data screening, global distribution, collaborative networks and the evolution of research hotspots. ABSTRACT Allergic rhinitis (AR) is driven by a network of inflammatory mediators released by mast cells ...
Shanshan Jing, Fengying Zhang, Qiqi Liu
wiley   +1 more source

Effects of the Indoor Environment on the Fraction of Exhaled Nitric Oxide in School-Aged Children

Canadian Respiratory Journal, 2009
BACKGROUND: The fractional concentration of exhaled nitric oxide (FeNO) appears to be a good marker for airway inflammation in children with asthma.
Thomas A Kovesi, Robert E Dales
doaj   +1 more source

Nebulization of the acidified sodium nitrite formulation attenuates acute hypoxic pulmonary vasoconstriction

Respiratory Research, 2010
Background Generalized hypoxic pulmonary vasoconstriction (HPV) occurring during exposure to hypoxia is a detrimental process resulting in an increase in lung vascular resistance. Nebulization of sodium nitrite has been shown to inhibit HPV.
Surber Mark W, Hoglen Niel C, Elliott Garry T, Dahal Bhola K, Schermuly Ralph T, Egemnazarov Bakytbek, Weissmann Norbert, Grimminger Friedrich, Seeger Werner, Ghofrani Hossein A   +9 more
doaj   +1 more source

Betaine‐, xylitol‐, and extra virgin olive oil–based toothpaste modulates inflammation and oral nitric oxide pathway: Clinical trial in gingivitis

Journal of Periodontology, EarlyView.
Abstract Background Gingivitis is a prevalent and reversible inflammatory condition driven by microbial dysbiosis. Beyond plaque control, interest has grown in oral hygiene formulations capable of modulating inflammation while preserving key microbial functions. Extra virgin olive oil (EVOO), together with xylitol and betaine, has demonstrated clinical
Francisco Mesa, Alejandro Rodríguez‐Agurto, Marco Bonilla, Debora Rodríguez‐Vilaboa, Beatriz Rodríguez‐Vilaboa, Manuel Bravo   +5 more
wiley   +1 more source

Exhaled Nitric Oxide and Nitric Oxide Synthase Expression in Hodgkin's Disease [PDF]

International Journal of Immunopathology and Pharmacology, 2009
Hodgkin's disease (HD) is a malignant lymphoma with frequent mediastinal involvement, characterized by a significant inflammatory infiltration. Exhaled Nitric Oxide (F E NO), is present in healthy humans, and has been proven to be increased in eosinophilic diseases such as allergic asthma. We
Guida G, Culla B, Scirelli T, Bellone G, Sciascia S, Brussino L, Novero D, Palestro G, HEFFLER, ENRICO MARCO, Gavarotti P, Rolla G, Bucca C.   +11 more
openaire   +3 more sources