Results 161 to 170 of about 321,704 (306)

Editorial: TGF-β and T cell biology

open access: yesFrontiers in Immunology, 2023
Saïdi Soudja, Nu Zhang
doaj   +1 more source

A Multidimensional Engineering Strategy Reprograms Microglia via Targeted and Sustained‐Release Extracellular Vesicles for Spinal Cord Injury Repair

open access: yesAdvanced Science, EarlyView.
A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong   +17 more
wiley   +1 more source

Electropulse‐Driven Dislocation Evolution in Sub‐10 nm Metallic Nanocrystals

open access: yesAdvanced Science, EarlyView.
Atomic‐scale TEM imaging reveals how nanosecond electropulses drive dislocation evolution in sub‐10 nm metallic nanocrystals. Enhanced electron scattering at structural heterogeneities nucleates dislocation loops and dipoles, which then repeatedly interact and annihilate, causing dislocation density fluctuations or structural disordering.
Youran Hong   +6 more
wiley   +1 more source

Inverse Design of Pre‐Strain via a Predictive Electromechanical Model for Enhanced Strain Sensing

open access: yesAdvanced Science, EarlyView.
An analytical electromechanical model rooted in microcrack evolution mechanics is globally calibrated from only eight pre‐strain datasets, enabling prediction of the complete sensing response at untested pre‐strain values within the calibrated design space (R2 > 0.99).
Jia‐Chen Shang   +10 more
wiley   +1 more source

Factsheet: Avoid Heat, Stroke & Exhaustion

open access: yes
AVOID SPOT TREAT HEAT STROKE & HEAT EXHAUSTION ...

core  

Perceived Time Shapes Physical Fatigue Accumulation and Its Neural Oscillatory Correlates

open access: yesAdvanced Science, EarlyView.
Can a clock change the course of physical fatigue? By covertly manipulating the clock calibration during repeated isometric contractions, we showed that perceived time shapes fatigue accumulation and frontal oscillatory dynamics. While fatigue accumulation was only reduced when the clock was slowed down, frontal oscillatory dynamics followed perceived ...
Pierre‐Marie Matta   +3 more
wiley   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li   +9 more
wiley   +1 more source

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