Results 101 to 110 of about 828,499 (287)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Results of the archeological investigations of settlement Zarechenskoe 1 in 2013–2014

open access: yesПоволжская археология, 2015
The results of the archeological investigations of the Zarechenskoe 1 settlement site (territory of Zarechnyi town, Penza oblast, Russian Federation) in 2013 and 2014 are represented in the article.
Vinnichek Vladimir A., Kireeva Karina M.
doaj  

Research students exhibition catalogue 2011 [PDF]

open access: yes, 2011
The catalogue demonstrates the scope and vibrancy of current inquiries and pays tribute to the creative capacity and investment of UCA research students.
Ayling-Smith, Beverly   +15 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Afghanistan: A Glimpse of War—Contemporary History at the Canadian War Museum [PDF]

open access: yes, 2012
How do you exhibit the history of an ongoing conflict, with an unknown outcome and with most documents restricted on the basis of operational security? What story can you tell?
Burtch, Andrew
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Green credit, tourism technology innovation, and sustainable development of tourism

open access: yesInternational Review of Economics & Finance
The research employs datasets spanning from 2010 to 2022, encompassing 31 provinces in China, to assess how green credit and technological innovations in tourism influence the sustained growth of the tourism sector.
Jingyu Sun, Dan Chen
doaj   +1 more source

A Postcard from Stuttgart: Rudolf Steiner's 150th anniversary exhibition 'Kosmos' [PDF]

open access: yes, 2011
It is easy to imagine that Rudolf Steiner (1861­‐1925) would be delighted with the new exhibition 'Kosmos Rudolf Steiner' at Stuttgart's modernistic Kunstmuseum. Kosmos is a major retrospective exhibition of Steiner's life and ideas.
Paull, John
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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