Results 101 to 110 of about 878,552 (336)

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Magnetic Microrobots for In Vivo Cargo Delivery: A Review

open access: yesMicromachines
Magnetic microrobots, with their small size and agile maneuverability, are well-suited for navigating the intricate and confined spaces within the human body.
Jialin Lin, Qingzheng Cong, Dandan Zhang
doaj   +1 more source

Exploring, Engaging, Understanding in Museums [PDF]

open access: yes, 2006
Patterns of accessibility through the space of the exhibition, connections or separations among spaces or exhibition elements, sequencing and grouping of elements, form our perceptions and shape our understanding.
Dalton, Ruth   +2 more
core  

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Results of the archeological investigations of settlement Zarechenskoe 1 in 2013–2014

open access: yesПоволжская археология, 2015
The results of the archeological investigations of the Zarechenskoe 1 settlement site (territory of Zarechnyi town, Penza oblast, Russian Federation) in 2013 and 2014 are represented in the article.
Vinnichek Vladimir A., Kireeva Karina M.
doaj  

LaPr3Ni3O9.76 as a candidate solid oxide fuel cell cathode: Role of microstructure and interface structure on electrochemical performance

open access: yesAPL Materials, 2019
A new higher-order Ruddlesden-Popper phase composition LaPr3Ni3O9.76 was synthesised by a sol-gel route and studied for potential intermediate-temperature solid oxide fuel cell cathode properties by electrochemical impedance spectroscopy.
Mudasir A. Yatoo   +2 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

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