Results 81 to 90 of about 53,865 (267)

Results of the archeological investigations of settlement Zarechenskoe 1 in 2013–2014

open access: yesПоволжская археология, 2015
The results of the archeological investigations of the Zarechenskoe 1 settlement site (territory of Zarechnyi town, Penza oblast, Russian Federation) in 2013 and 2014 are represented in the article.
Vinnichek Vladimir A., Kireeva Karina M.
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

RGB Approach for Pixel-Wise Identification of Cellulose Nitrate Photo Negative Yellowing

open access: yesHeritage
Film-based cellulose nitrate negatives are a unique class of objects that contain important information about life, historical buildings, and the natural landscapes of past years.
Anastasia Povolotckaia   +7 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Diagnostic Dilemma of an Unusual Pelvic Mass in a Young Girl

open access: yesJournal of Nepal Medical Association, 2007
Swaraj Rajbhandari, B Shrestha, A Karki
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Source Term-Based Synthetic Turbulence Generator Applied to Compressible DNS of the T106A Low-Pressure Turbine

open access: yesInternational Journal of Turbomachinery, Propulsion and Power
Direct numerical simulations (DNSs) of the T106A low-pressure turbine were conducted for various turbulence intensities and length scales to investigate their effects on flow behaviour and transition.
João Isler   +7 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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