Results 61 to 70 of about 53,865 (267)
LandThe construction of China’s national park system is an important part of the ecological civilization development strategy, and the behavior of the subjects in the national park has a great impact on its sustainable development.
Yechen Zhang +4 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The Nitrate Cellulose Negatives: Degradation Study via Chemometric Methods
HeritagePhotographic artifacts carry important historical and cultural information. Materials used in photography at the turn of the XIXth and XXth centuries tend to degrade both over time and if the temperature and humidity conditions of storage are violated ...
Anastasia Povolotckaia +7 more
doaj +1 more source
E-Journal of Chemistry, 2012 A liquid chromatographic method was developed and validated for the simultaneous determination of ciprofloxacin hydrochloride and dexamethasone sodium phosphate in bulk and pharmaceutical formulations.
Prakash Katakam, Karanam R. Sireesha
doaj +1 more source
A composite hydrogel for brain tissue phantoms
Materials & Design, 2016 Synthetic phantoms are valuable tools for training, research and development in traditional and computer aided surgery, but complex organs, such as the brain, are difficult to replicate.
Antonio E. Forte +4 more
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Exhibition Reviews in the Time of COVID-19
Panorama, 2022 The Panorama Exhibition Reviews Editors
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source