Results 61 to 70 of about 828,499 (287)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
boredomresearch exhibited the Real Snail Mail installation in Process as Paradigm Exhibition, LABoral Centro de Arte y Creacion, Gijon Spain (23rd April - 30th Aug 2010).
boredomresearch, +2 more
core
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Giorgione [exhibition review] [PDF]
Exhibition review of In the Age of Giorgione (London, Royal Academy of ...
Nichols, Tom
core
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
The feasibility of reaching gigatonne scale CO2 storage by mid-century
The Sixth Assessment Report by the Intergovernmental Panel on Climate Change projects subsurface carbon storage at rates of 1 – 30 GtCO2 yr−1 by 2050.
Yuting Zhang +2 more
doaj +1 more source
Sporting was an exhibition held at Demo at Auckland. The exhibition featured the artists Christina Read Danielle Foster Jack Hadley Joshua Harris-Harding Lucy Meyle Kate Russell Hannah Valentine and was hosted by ...
Foster, Jordan
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The construction of China’s national park system is an important part of the ecological civilization development strategy, and the behavior of the subjects in the national park has a great impact on its sustainable development.
Yechen Zhang +4 more
doaj +1 more source

