Results 61 to 70 of about 863,856 (339)

Experimental investigation of the viscoplastic behaviours and microstructure evolutions of AZ31B and Elektron 717 Mg-alloys

open access: yesMaterials & Design, 2019
An insight into the thermo-mechanical behaviours of AZ31B and Elektron 717 magnesium alloys under the hot stamping conditions was established. High-temperature tensile tests (i.e.
Kai Zhang   +6 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Sporting [PDF]

open access: yes, 2018
Sporting was an exhibition held at Demo at Auckland. The exhibition featured the artists Christina Read Danielle Foster Jack Hadley Joshua Harris-Harding Lucy Meyle Kate Russell Hannah Valentine and was hosted by ...
Foster, Jordan
core  

Evolution of twinning and shear bands in magnesium alloys during rolling at room and cryogenic temperature

open access: yesMaterials & Design, 2020
Twinning and shear bands are two main deformation structures in magnesium alloys at low temperatures, however, the relationship between these two deformation structures is still under debate.
Kai Zhang   +4 more
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Real Snail Mail [PDF]

open access: yes, 2008
boredomresearch exhibited the Real Snail Mail installation in Process as Paradigm Exhibition, LABoral Centro de Arte y Creacion, Gijon Spain (23rd April - 30th Aug 2010).
boredomresearch,   +2 more
core  

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

BAD CURATION: Exhibiting Degenerate Art [PDF]

open access: yes, 2017
In a time of censorship and social control under the ideology of the Nazi regime, Hitler and his counterparts produced an exhibition to discredit artistic developments deemed inappropriate and counterproductive for society. This project analyzed the \u27\
Colletti, Hannah
core   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

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