Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Research on the application of digital media technology in museum exhibition design: A case study of the national museum of Singapore [PDF]
There is a profound transformation in museum exhibition design. The ubiquitous digital media technology is driving the rapid evolution and development of museums.
Dong Shuang
doaj +1 more source
Design of Displays and Exhibitions
In discussing exhibition design from my perspective as a designer I thought it would be worthwhile to give my definitions of design, exhibitions, and finally, to present a short formula for developing exhibitions. I have assumed that such exhibitions would be developed by a designer and an 'expert' working together. Sometimes this is not practical with
openaire +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Study of technical standards for Projection Mapping in advertising events
Projection Mapping are considered a technological innovation that allows designers to be able to make drawings or videos to unite with any surface like buildings or roads, projection shows have many phases, these phases start with pre-production process ...
Prof. Magdy Abd elaziz Emam +2 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
My Exhibition: una piattaforma per fare la storia delle mostre
For this issue of MMD, the editorial committee has decided to give a voice to those who provide institutional recognition to essential yet often overlooked figures in the cultural and museum landscape.
Alessandro Lolli
doaj +1 more source
Exhibiting coins as economic artefacts: Curating historical interpretation in Faith and Fortune: visualizing the divine on Byzantine and early Islamic coinage (Barber Institute of Fine Arts, Birmingham, November 2013-January 2015) [PDF]
Faith and Fortune: visualizing the divine on Byzantine and early Islamic coins was an exhibition at the Barber Institute of Fine Arts (October 2013-January 2015).
Rebecca Darley, Daniel Reynolds
doaj

