Results 61 to 70 of about 203,466 (305)

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

open access: yes
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja   +8 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Viable Airborne and Deposited Microorganisms inside the Historical Museum of Crete

open access: yesAerosol and Air Quality Research, 2021
Measurements of the ambient viable microbe concentrations and of the microbial deposits on surfaces were performed in the Historical Museum of Crete over a period of two years.
Eleftheria Katsivela   +2 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

THE INSTITUTE OF THE EARTH’S CRUST MUSEUM TODAY

open access: yesГеодинамика и тектонофизика, 2015
In the past five years, the Institute of the Earth’s Crust Museum has considerably increased its exhibition space and the collection of objects. The Museum documents the history of the Institute since 1949.
L. А. Ivanova
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Exhibits that matter: material gestures with theoretical stakes in Behind the Green Door and 1:1 Stijlkamers [PDF]

open access: yes, 2015
This paper engages with theory in architectural exhibitions and with hybrid architectural practices that combine design and building with research and curating.
Liefooghe, Maarten
core   +1 more source

The importance of long-term hygrothermal assessment of museum spaces: method and application in a permanent exhibition in a historical building

open access: yesConservar Património, 2019
This paper presents the analysis of the hygrothermal conditions of a museum space hosted in an 18th century building, in Coimbra (Portugal). This historical building, which houses the Science Museum of the University of Coimbra, is located in the ...
Luísa Dias Pereira   +3 more
doaj   +1 more source

La collection de machines orthopédiques de François Humbert (1776-1850), médecin meusien, fondateur du premier établissement orthopédique français

open access: yesIn Situ, 2017
The early nineteenth century can be considered as a turning point in orthopaedics. Scientific and technical progress allowed those who were called ‘lame’ and ‘hunchbacks’ to be given new treatments.
Antoine Desseaux   +3 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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