Results 71 to 80 of about 203,466 (305)

Rycotewood College: report from the Inspectorate (FEFC inspection report; 22/95 and 73/99) [PDF]

open access: yes, 1999
The Further Education Funding Council has a legal duty to make sure further education in England is properly assessed. The FEFC’s inspectorate inspects and reports on each college of further education according to a four-year cycle. This record comprises

core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Boston Hospitality Review: Spring 2013 [PDF]

open access: yes, 2013
Lodging Update: Providence, Rhode Island by Rachel Roginsky and Matthew Arrants -- Brand Heritage and Heritage Tourism by Bradford Hudson -- Te Front Desks of Boston by Michael Oshins -- Defining the New Luxury: Perspectives from Industry Leaders by ...
Arrants, Matthew   +6 more
core   +1 more source

L’invention de la préhistoire par les objets

open access: yesLes Nouvelles de l’Archéologie, 2012
The archaeological collections which Jacques Boucher de Perthes 1788-1868) sent in 1860 to the National natural history museum, remain little known.
Rachel Orliac
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

The Utopian [PDF]

open access: yes, 2010
The paper was concerned with the future of the social housing complex in Poplar, East London called Robin Hood Gardens designed, conceived and built in the late 60's by Alison and Peter Smithson. The project and publication centred on the possible future
Mifsud, Daniel, Roberts, Christopher
core   +1 more source

Preventive conservation strategies for sustainable urban pollution control in museums [PDF]

open access: yes, 2000
The last 40 years have seen major changes in the sources and concentrations of urban pollution (nitrogen dioxide, sulfur dioxide, hydrogen sulfide, and particulates).
Blades, N   +3 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Perspetivas sobre a representação das monções no Museu Paulista e no Museu Republicano de Itu

open access: yesMidas: Museus e Estudos Interdisciplinares, 2019
The article examines the appropriation of nineteenth-century scientific illustrator’s works – produced during the Langsdorff expedition (1825-1829) – by Afonso d’Escragnolle Taunay (1876-1958) during his time as director of the Museu Paulista in São ...
Maria Aparecida de Menezes Borrego
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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