Results 111 to 120 of about 285,101 (303)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

EXHIBITION AND NOTICES

open access: yesProceedings of the Zoological Society of London, 1912
(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
openaire   +3 more sources

Artists’ books in HE teaching and learning [PDF]

open access: yes, 2012
Learning resource, teaching collection, study collection, research collection or special collection: a historical collection of artists’ books like that at Chelsea College of Art & Design Library can (and probably, has) been used and referred to in all ...
Grandal Montero, Gustavo
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Language of Memory [PDF]

open access: yes, 2015
Language of Memory centres on Whitney McVeigh’s short film 'Birth’: Origins at the end of Life, recording six women’s experience of birth and existence, in the setting of St Christopher’s Hospice, London. The simple yet poignant film is enveloped by work
McVeigh, Whitney
core  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Exhibiting Yugoslavia [PDF]

open access: yesDružboslovne Razprave, 2015
V pričujočem prispevku s pomočjo teoretskega pojmovanja spomina, kritične analize diskurza in multimodalne analize analiziramo narativne elemente razstave "Jugoslavija: od začetka do konca", ki je bila postavljena v beograjskem Muzeju jugoslovanske zgodovine, pri čemer identificiramo in analiziramo muzejske diskurze v postjugoslovanski tranzicijski ...
openaire   +3 more sources

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