Results 71 to 80 of about 285,101 (303)

From Learning to Rationalization: the Roles of Accounting in the Management of Parisian Great Exhibitions from 1853 to 1902 [PDF]

open access: yes
During the second half of the nineteenth century, five Great Exhibitions took place in Paris. The French state was highly involved in their financing and management which led to the implementation of public finance rules.
Céline Michaïlesco, Karine Fabre
core  

Converting Family Into Fans: How the Comtemporary Jewish Museum Expanded Its Reach [PDF]

open access: yes, 2016
The last in a series of 10 case studies explores how The Contemporary Jewish Museum in SanFrancisco worked to attract families of all backgrounds and build the next generation of museum supporters.
Bob Harlow, Cindy Cox Roman
core  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Thin Black Line(s) [PDF]

open access: yes, 2011
Thin Black Line(s) focuses on the contribution of Black and Asian women artists to British art in the 1980s. Taking as its starting point three seminal exhibitions curated by artist Lubaina Himid in London from 1983 to 1985, the display charts the coming
Himid, Lubaina
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Engaging the Entire Community: A New Role for Permanent Collections [PDF]

open access: yes, 1999
Discusses the strategies several museums are using -- such as creative partnerships with churches, schools, businesses and community organizations -- to help draw in people, many from untapped ...

core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Mapping the Design Criterion Framework for Museum Exhibition Design Project [PDF]

open access: yes, 2009
Currently, museums are struggling to develop and present their expertise by focusing on the interactive relationship with museum visitors. In order to meet the needs of museum exhibitions, an efficient and workable design process is of primary importance
Lin, Chunghung
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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