Results 111 to 120 of about 8,161,835 (383)
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
FEBS Letters, EarlyView.Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää +2 more
wiley +1 more source
The Event of Faith: The Transformation of Philosophy by Theology in Rudolf Bultmann
Open Theology, 2019 This article suggests that Rudolf Bultmann can be seen to reconfigure Heidegger’s understanding of the relationship between philosophy and theology in terms of a transformation of philosophy by theology. In that sense, though Bultmann is often understood
Deketelaere Nikolaas
doaj +1 more source
Rainbow Matchings: existence and counting
, 2011 A perfect matching M in an edge-colored complete bipartite graph K_{n,n} is rainbow if no pair of edges in M have the same color. We obtain asymptotic enumeration results for the number of rainbow matchings in terms of the maximum number of occurrences ...
Perarnau, Guillem, Serra, Oriol
core +1 more source
Digital Existence, 2018 This chapter will engage with the notion that one of the key defining features of digital being, at least in terms of ethical engagement with others via technological interfaces and networks, is a heightened state of both invulnerability and ...
Amanda Lagerkvist
semanticscholar +1 more source
Rewriting the dendritic cell code in cancer—from subset identity to immunotherapeutic design
FEBS Letters, EarlyView.Dendritic cells (DCs) play central roles in cancer immunity but are often subverted by the tumor microenvironment. This review explores the diversity of DC subsets, their functional plasticity, and emerging therapeutic strategies to reprogram DCs for enhanced antitumor responses, including vaccines, in vivo targeting, and DC‐based immunotherapies ...
Estevão Carlos Silva Barcelos +3 more
wiley +1 more source
Stochastic Entropy Solutions for Stochastic Nonlinear Transport Equations
Entropy, 2018 This paper considers the existence and uniqueness of stochastic entropy solution for a nonlinear transport equation with a stochastic perturbation. The uniqueness is based on the doubling variable method.
Rongrong Tian, Yanbin Tang
doaj +1 more source
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
A One Line Derivation of EGARCH
Econometrics, 2014 One of the most popular univariate asymmetric conditional volatility models is the exponential GARCH (or EGARCH) specification. In addition to asymmetry, which captures the different effects on conditional volatility of positive and negative effects of ...
Michael McAleer, Christian M. Hafner
doaj +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
FEBS Letters, EarlyView.Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli +10 more
wiley +1 more source