Global existence and blowup for free boundary problems of coupled reaction-diffusion systems
This article concerns a free boundary problem for a reaction-diffusion system modeling the cooperative interaction of two diffusion biological species in one space dimension.
Jianping Sun +3 more
doaj
Can existence benefit or harm a person? I argue that it cannot. In order for existence to harm a person it has to be the case that existence is worse for the person than never existing. This claim could only be true if it is understood as a claim about the actual, extrinsic value of existence for a person.
openaire +3 more sources
On the existence of pure strategy equilibria in large generalized games with atomic players [PDF]
We consider a game with a continuum of players where only a finite number of them are atomic. Objective functions and admissible strategies may depend on the actions chosen by atomic players and on aggregate information about the actions chosen by non ...
Riascos Villegas, Alvaro +1 more
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
On the existence of a Ramsey equilibrium with endogenous labor supply and borrowing constraints [PDF]
In this paper, we study the existence of an intertemporal equilibrium in a Ramsey model with heterogenous discounting, elastic labor supply and borrowing constraints.
Stefano Bosi, Cuong Le Van
core +2 more sources
Positive solutions for a class of singular boundary-value problems
Using regularization and the sub-super solutions method, this note shows the existence of positive solutions for singular differential equation subject to four-point boundary conditions.
Li Xia, Zhengan Yao
doaj
Existence of Solutions for a Hadamard Fractional Boundary Value Problem at Resonance
We explore the existence of solutions for a Hadamard fractional differential equation, subject to nonlocal boundary conditions, which contain Hadamard fractional derivatives and Riemann–Stieltjes integrals.
Rodica Luca, Alexandru Tudorache
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Existence of competitive equilibrium in a single-sector growth model with heterogeneous agents and endogenous leisure [PDF]
We prove the existence of competitive equilibrium in a single-sector dynamic economy with heterogeneous agents and elastic labor supply. The method of proof relies on exploiting the existence of Lagrange multipliers in infinite dimensional spaces and the
Cuong Le Van, Manh-Hung Nguyen
core
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source

