Results 141 to 150 of about 2,776,395 (308)
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Existence of Solutions in Continuous-time Optimal Growth Models [PDF]
This paper studies the existence of solutions in continuous time optimization problems. It provides a theorem whose conditions can be easily checked in most models of the optimal growth theory, including those with increasing returns and multi-sector ...
Cuong Le Van +2 more
core
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Limit cycles for a class of polynomial systems and applications
In this paper, we study the existence and uniqueness of limit cycles for a particular polynomial system. Some known results are extended and improved.
Hanying Feng +3 more
doaj
On equilibrium existence with endogenous restricted financial participation [PDF]
Allowing for durable commodities, we prove equilibrium existence in an abstract incomplete market economy with endogenous restricted financial participation without requiring financial survival assumptions.
Abdelkrim Seghir +1 more
core
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
CO-EXISTENCE COSTS UNDER GERMAN REGULATION - CASE STUDIES OF BT MAIZE [PDF]
Paper prepared for presentation at the 10th ICABR International Conference on Agricultural Biotechnology: Facts, Analysis and Policies Ravello (Italy), June 29th to July 2nd, 2006Co-existence measure, GMO, Bt maize, GIS, Germany, Agricultural and Food ...
Menrad, Klaus, Reitmeier, Daniela
core
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Everything exists, therefore God exists as the cause of the Exist of Everything..pdf
Logic ...
openaire +2 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source

