Results 111 to 120 of about 2,837,333 (257)

Existence and Stability of Neutral Stochastic Impulsive and Delayed Integro-Differential System via Resolvent Operator

open access: yesFractal and Fractional
In this paper, we present the existence of a mild solution for a class of a neutral stochastic integro-differential system over a Hilbert space. Such systems are influenced by both multiplicative and fractional noise, alongside non-instantaneous impulses,
Hamza Khalil   +3 more
doaj   +1 more source

A Note on Existence of Nash Networks in One-way Flow [PDF]

open access: yes
In this note we provide conditions which ensure the existence of Nash networks in One-way flow models with cost heterogeneity.
Pascal Billand   +2 more
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Global conservation of phylogenetic diversity captures more than just functional diversity

open access: yesNature Communications, 2019
Nisha R. Owen   +3 more
doaj   +1 more source

CO-EXISTENCE COSTS UNDER GERMAN REGULATION - CASE STUDIES OF BT MAIZE [PDF]

open access: yes
Paper prepared for presentation at the 10th ICABR International Conference on Agricultural Biotechnology: Facts, Analysis and Policies Ravello (Italy), June 29th to July 2nd, 2006Co-existence measure, GMO, Bt maize, GIS, Germany, Agricultural and Food ...
Menrad, Klaus, Reitmeier, Daniela
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Existence of Solutions in Continuous-time Optimal Growth Models [PDF]

open access: yes
This paper studies the existence of solutions in continuous time optimization problems. It provides a theorem whose conditions can be easily checked in most models of the optimal growth theory, including those with increasing returns and multi-sector ...
Cuong Le Van   +2 more
core  

Existence of solutions for nonlinear parabolic problems [PDF]

open access: yes, 1999
summary:We consider nonlinear parabolic boundary value problems. First we assume that the right hand side term is discontinuous and nonmonotone and in order to have an existence theory we pass to a multivalued version by filling in the gaps at the ...
Papageorgiou, N   +3 more
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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