Results 141 to 150 of about 8,396,811 (368)

A Singular nonlinear problems with natural growth in the gradient

Mathematical Modelling and Analysis
In this paper, we consider the equation  with boundary conditions where  is an open bounded subset of is a Leray-Lions operator defined on is a characteristic function, and is a Carathéodory function such thatsign Forand sufficiently small, we prove ...
Boussad Hamour
doaj   +1 more source

Existence and multiplicity of positive solutions for a system of fractional differential equation with parameters [PDF]

, 2017
Xiaoling Han, Xiaojuan Yang
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Global conservation of phylogenetic diversity captures more than just functional diversity

Nature Communications, 2019
Nisha R. Owen, Rikki Gumbs, Claudia L. Gray, Daniel P. Faith   +3 more
doaj   +1 more source

On a Class of Nonlinear Elliptic Equations with General Growth in the Gradient

Mathematics
In this paper, we prove an existence and uniqueness result for a class of Dirichlet boundary value problems whose model is −Δpu=β|∇u|q+c|u|p−2u+fin Ω,u=0on ∂Ω, where Ω is an open bounded subset of RN, N≥2 ...
M. Francesca Betta, Anna Mercaldo, Roberta Volpicelli   +2 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Global existence and blowup for free boundary problems of coupled reaction-diffusion systems

Electronic Journal of Differential Equations, 2014
This article concerns a free boundary problem for a reaction-diffusion system modeling the cooperative interaction of two diffusion biological species in one space dimension.
Jianping Sun, Haihua Lu, Shuanglong Gan, Lang Chen   +3 more
doaj  

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Positive solutions for a class of singular boundary-value problems

Electronic Journal of Differential Equations, 2007
Using regularization and the sub-super solutions method, this note shows the existence of positive solutions for singular differential equation subject to four-point boundary conditions.
Li Xia, Zhengan Yao
doaj