Results 141 to 150 of about 7,948,884 (384)

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

THE EXISTENCE OF TWO FORMS OF HYPERTENSIN [PDF]

open access: bronze, 1954
Leonard T. Skeggs   +3 more
openalex   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

open access: yesMolecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić   +31 more
wiley   +1 more source

Existence

open access: yesCrítica (México D. F. En línea), 1984
En la sección I hago un análisis parcial de los conceptos normales de existencia, en parte para hacer una evaluación de la posición de Murray Kiteley sobre la existencia en “Is Existence a Predicate?”. Él correctamente argumenta que ‘existencia’ tiene dos usos importantes, uno de los cuales —el uso llamado “no excluyente” (‘existencia1’)— no es un ...
openaire   +3 more sources

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

Maximum and minimum principles for nonlinear transport equations on discrete-space domains

open access: yesElectronic Journal of Differential Equations, 2014
We consider nonlinear scalar transport equations on the domain with discrete space and continuous time. As a motivation we derive a conservation law on these domains.
Jonas Volek
doaj  

Foreword: Speaking Existence [PDF]

open access: yes
[[issue ...
Joan Chiung-huei Chang   +1 more
core  

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

Existence and uniqueness of local weak solutions for the Emden-Fowler wave equation in one dimension

open access: yesElectronic Journal of Differential Equations, 2015
In this article we consider the existence and uniqueness of local weak solutions to the Emden-Fowler type wave equation $$ t^ 2 u_{tt} -u_{{xx}}=|u|^{p-1}u\quad\text{in }[1,T]\times (a,b) $$ with initial-boundary value conditions in a finite time ...
Meng-Rong Li
doaj  

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

open access: yesMolecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang   +8 more
wiley   +1 more source

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