Results 141 to 150 of about 8,161,835 (383)

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

INSANITY AND PHTHISIS, THEIR TRANSMUTATION, CONCURRENCE AND CO-EXISTENCE [PDF]

, 1895
H. A. TOMLINSON
openalex   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Maximum and minimum principles for nonlinear transport equations on discrete-space domains

Electronic Journal of Differential Equations, 2014
We consider nonlinear scalar transport equations on the domain with discrete space and continuous time. As a motivation we derive a conservation law on these domains.
Jonas Volek
doaj  

** On the existence of nonconvex polygons of a prescribed type [PDF]

, 1947
Josef Brejcha
openalex   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Existence and uniqueness of local weak solutions for the Emden-Fowler wave equation in one dimension

Electronic Journal of Differential Equations, 2015
In this article we consider the existence and uniqueness of local weak solutions to the Emden-Fowler type wave equation $$ t^ 2 u_{tt} -u_{{xx}}=|u|^{p-1}u\quad\text{in }[1,T]\times (a,b) $$ with initial-boundary value conditions in a finite time ...
Meng-Rong Li
doaj  

THE EXISTENCE OF TWO FORMS OF HYPERTENSIN [PDF]

, 1954
Leonard T. Skeggs, Walton H. Marsh, Joseph R. Kahn, Norman P. Shumway   +3 more
openalex   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Existence

Crítica (México D. F. En línea), 1984
En la sección I hago un análisis parcial de los conceptos normales de existencia, en parte para hacer una evaluación de la posición de Murray Kiteley sobre la existencia en “Is Existence a Predicate?”. Él correctamente argumenta que ‘existencia’ tiene dos usos importantes, uno de los cuales —el uso llamado “no excluyente” (‘existencia1’)— no es un ...
openaire   +3 more sources