Results 141 to 150 of about 6,731,721 (317)
Non-existence does not exist. [PDF]
Notre Dame Journal of Formal Logic, 1970 openaire +2 more sources
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Global solutions to a one-dimensional nonlinear wave equation derivable from a variational principle
Electronic Journal of Differential Equations, 2017 This article focuses on a one-dimensional nonlinear wave equation which is the Euler-Lagrange equation of a variational principle whose Lagrangian density involves linear terms and zero term as well as quadratic terms in derivatives of the field.
Yanbo Hu, Guodong Wang
doaj
CLXXIX.—The relation between viscosity and chemical constitution. Part II. The existence of racemic compounds in the liquid state [PDF]
, 1908 Albert Ernest Dunstan +1 more
openalex +1 more source
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
LIV.—Existence of racemic compounds in the liquid state [PDF]
, 1913 Alec Duncan Mitchell, Clarence Smith
openalex +1 more source
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
On the Probable Existence of a considerable Fault in the Lias near Rugby, and of a new Outlier of the Oolite [PDF]
, 1875 J. M. Wilson
openalex +1 more source
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source