Results 151 to 160 of about 7,948,884 (384)

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

open access: yesMolecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad   +13 more
wiley   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

On existence theorems

open access: yesDiscrete Mathematics, 1993
AbstractWe discuss the question of constructive proofs, or polynomial-time algorithms, for theorems which were proved earlier nonconstructively. We present a formal model for such statements and give a collection of examples. In a greater detail, we deal with the problem of finding another Hamiltonian cycle in a cubic graph provided that one cycle is ...
openaire   +2 more sources

Robotic tele-existence [PDF]

open access: yes
Tele-existence is an advanced type of teleoperation system that enables a human operator at the controls to perform remote manipulation tasks dexterously with the feeling that he or she exists in the remote anthropomorphic robot in the remote environment.
Arai, Hirohiko   +2 more
core   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

On the existence and functionality of topologically associating domains

open access: yesNature Genetics, 2020
Jonathan A. Beagan   +1 more
semanticscholar   +1 more source

Existence and non existence of capillary surfaces

open access: yesManuscripta Mathematica, 1979
A general criterion for existence of solutions of the capillary equation, introduced by Concus and Finn [1] and by Giusti [7], is shown to be equivalent to the question of existence of certain vector fields. The result is applied to particular boundary configurations, and it is shown that in some cases the local “corner condition” of [1] is both ...
openaire   +2 more sources

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Global conservation of phylogenetic diversity captures more than just functional diversity

open access: yesNature Communications, 2019
Nisha R. Owen   +3 more
doaj   +1 more source

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