Results 181 to 190 of about 6,496,822 (268)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Quantum spin liquid from electron-phonon coupling. [PDF]

Proc Natl Acad Sci U S A
Cai X, Han Z, Li ZX, Kivelson SA, Yao H.
europepmc   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Fluid Relaxation Approximation of the Busenberg-Travis Cross-Diffusion System. [PDF]

Commun Math Phys
Carrillo JA, Chen X, Du B, Jüngel A.
europepmc   +1 more source

A history of the game birds, wild-fowl and shore birds of Massachusetts and adjacent states; with observations on their recent decrease in numbers; also the means for conserving those still in existence,

, 1912
Edward Howe Forbush, Willey Ingraham Beecroft, Louis Agassiz Fuertes, Herbert Keightley Job   +3 more
openalex   +2 more sources

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Nash Equilibria in Four-Strategy Quantum Extensions of the Prisoner's Dilemma Game. [PDF]

Entropy (Basel)
Frąckiewicz P, Gorczyca-Goraj A, Grzanka K, Nowakowska K, Szopa M.   +4 more
europepmc   +1 more source

XV. Further considerations on the existence of a fourth imponderable [PDF]

John William Draper
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Synchronization and dynamics of modified fractional order Kawasaki disease model with chaos stability control. [PDF]

Sci Rep
Nisar KS, Farman M, Jamil K, Hincal E, Sambas A.   +4 more
europepmc   +1 more source