Results 61 to 70 of about 1,638,815 (287)

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Existence results for rational normal curves [PDF]

open access: yesarXiv, 2006
In this paper we study existence and uniqueness of rational normal curves in $\PP^n$ passing through $p$ points and intersecting $l$ codimension two linear spaces in $n-1$ points each. If $p+l=n+3$ and the points and the linear spaces are generic, one expects the curve to exist, but this is not always the case.
arxiv  

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Contre le pragmatisme en ontologie de la musique

open access: yesAisthesis, 2014
Pragmatism in the philosophy of music claims that “musical work” does not mean a kind of things in the world. For the Pragmatist, the title of a musical work does not designate a single entity in the world.
Roger Pouivet
doaj   +1 more source

Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren   +16 more
wiley   +1 more source

The Normalized Ricci Flow on Four-Manifolds and Exotic Smooth Structures [PDF]

open access: yesarXiv, 2008
In this article, we shall investigate the relationship between the existence or non-existence of non-singular solutions to the normalized Ricci flow and smooth structures on closed 4-manifolds, where non-singular solutions to the normalized Ricci flow are solutions which exist for all time $t \in [0, \infty)$ with uniformly bounded sectional curvature.
arxiv  

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

A Plankton allelopathic model described by a delayed quasilinear parabolic system

open access: yesMathematical Modelling and Analysis, 2012
The quasilinear parabolic system has been applied to a variety of physical and engineering problems. However, most works lack effective techniques to deal with the asymptotic stability.
Canrong Tian, Peng Zhu
doaj   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

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