Results 71 to 80 of about 55,115 (257)

Uniqueness Implies Existence on Time Scales [PDF]

, 2001
The uniqueness of solutions of initial value boundary value problems along with some uniqueness conditions on two-point boundary value problems imply the existence of solutions for the same boundary value problems for the second-order nonlinear dynamic ...
Chyan, Chuan Jen, 錢傳仁; Chyan, Chuan-jen   +1 more
core   +1 more source

New Existence and Uniqueness Results for Fractional Differential Equations

Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2013
In this paper, we study a class of boundary value problems of nonlinear fractional differential equations with integral boundary conditions. Some new existence and uniqueness results are obtained by using Banach fixed point theorem.
Anber Ahmed, Belarbi Soumia
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Stability analysis of an implicit fractional integro-differential equation via integral boundary conditions

Alexandria Engineering Journal
The primary objective of this research study is to analyze a boundary problem involving Caputo fractional integro-differential equations. The focus is on a differential equation with a nonlinear right-hand side composed of two terms.
Mehboob Alam, Akbar Zada, Thabet Abdeljawad   +2 more
doaj   +1 more source

ON EXISTENCE AND UNIQUENESS OF OPTIMAL CONTROLS

Demonstratio Mathematica, 1985
A quasilinear ordinary differential equation has coefficients which depend on a control function in a nonlinear manner. The trajectories are constrained at the beginning and the end of the control interval, and the performance criterion is quadratic in the state and the control; the admissible control functions are bounded above and below.
openaire   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Existence and uniqueness theorems on certain difference-differential equations

Electronic Journal of Differential Equations, 2009
In the present paper, existence and uniqueness theorems for the solutions of certain nonlinear difference-differential equations are established. The main tools employed in the analysis are based on the applications of the Leray-Schauder alternative ...
Baburao G. Pachpatte
doaj  

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A New Existence and Uniqueness Theorem for Continuous Games [PDF]

This paper derives a general sufficient condition for existence and uniqueness in continuous games using a variant of the contraction mapping theorem applied to mapping from a subset of the real line on to itself.
Seamus Hogan
core