Results 91 to 100 of about 500,030 (282)
On systems of continuity equations with nonlinear diffusion and nonlocal drifts
This paper is devoted to existence and uniqueness results for classes of nonlinear diffusion equations (or systems) which may be viewed as regular perturbations of Wasserstein gradient flows. First, in the case.
Carlier, Guillaume, Laborde, Maxime
core
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
On well-posedness for the Benjamin-Ono equation
We prove existence of solutions for the Benjamin-Ono equation with data in $H^s(\R)$, $s>0$. Thanks to conservation laws, this yields global solutions for $H^\frac 1 2(\R)$ data, which is the natural ``finite energy'' class.
Burq, N., Planchon, F.
core +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Optimal pair of fixed points: existence, uniqueness and approximation
In this paper, we introduce a novel class of mappings, referred to as noncyclic generalized θ-contractions. By employing the geometric concept of W U C $WUC$ property in metric spaces, we establish new existence and convergence theorems for the fixed ...
A. Safari-Hafshejani, M. Gabeleh
doaj +1 more source
Existence and uniqueness for a Ginzburg-Landau system for superconductivity
We prove the existence of a unique solution for a time-dependent Ginzburg-Landau model in superconductivity under the Coulomb gauge. Also we prove the uniform-in-$\epsilon$ well-posedness of the solution, where $\epsilon$ is the coefficient of the ...
Jishan Fan, Yong Zhou
doaj
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
In this article, we discuss the existence and uniqueness of solution to fractional order ordinary and delay differential equations. We apply our results on the single species model of Lotka Volterra type.
Syed Abbas
doaj

