Results 91 to 100 of about 201,556 (360)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Ulam–Hyers Stability and Uniqueness for Nonlinear Sequential Fractional Differential Equations Involving Integral Boundary Conditions

open access: yesFractal and Fractional, 2021
Fractional-order boundary value problems are used to model certain phenomena in chemistry, physics, biology, and engineering. However, some of these models do not meet the existence and uniqueness required in the mainstream of mathematical processes ...
Areen Al-khateeb   +3 more
doaj   +1 more source

Existence and Uniqueness of Equilibrium in a Reinsurance Syndicate [PDF]

open access: yesSSRN Electronic Journal, 2008
In this paper we consider a reinsurance syndicate, assuming that Pareto optimal allocations exist. Under a continuity assumption on preferences, we show that a competitive equilibrium exists and is unique. Our conditions allow for risks that are not bounded, and we show that the most standard models satisfy our set of sufficient conditions, which are ...
openaire   +4 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Existence Results for a Class of Fractional Differential Equations with Periodic Boundary Value Conditions and with Delay

open access: yesAbstract and Applied Analysis, 2013
We discuss the existence and uniqueness of solution for two types of fractional order ordinary and delay differential equations. Fixed point theorems are the main tool used here to establish the existence and uniqueness results.
Hadi Karami   +2 more
doaj   +1 more source

EXISTENCE AND UNIQUENESS RESULTS FOR VOLTERRA-FREDHOLM INTEGRO DIFFERENTIAL EQUATIONS

open access: yesAdvances in the Theory of Nonlinear Analysis and its Application, 2020
This paper establishes a study on some important latest innovations in the existence and uniqueness results by means of Banach contraction fixed point theorem for Caputo fractional Volterra-Fredholm integro-differential equations with boundary condition.
Ahmed A. Hamoud   +2 more
semanticscholar   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Uniqueness Implies Existence on Time Scales [PDF]

open access: yes, 2001
The uniqueness of solutions of initial value boundary value problems along with some uniqueness conditions on two-point boundary value problems imply the existence of solutions for the same boundary value problems for the second-order nonlinear dynamic ...
Chyan, Chuan Jen   +1 more
core   +1 more source

The existence of uniquely −G colourable graphs

open access: yesDiscrete Mathematics, 1998
Given graphs \(F\) and \(G\) and a nonnegative integer \(k\), a function \(\pi :V(F)\rightarrow \{1,\ldots ,k\}\) is a \(-G\) \(k\)-colouring of \(F\) if no induced copy of \(G\) is monochromatic; \(F\) is \(-G\) \(k\)-chromatic if \(F\) has a \(-G\) \(k\)-colouring but no \(-G\) \((k-1)\)-colouring.
Dimitris Achlioptas   +3 more
openaire   +1 more source

Existence and uniqueness results for a nonlinear Caputo fractional boundary value problem on a star graph

open access: yesJournal of Mathematical Analysis and Applications, 2019
In this paper, we study a nonlinear Caputo fractional boundary value problem on a star graph. By means of transformation, an equivalent system of fractional boundary value problem is obtained.
Vaibhav Mehandiratta   +2 more
semanticscholar   +1 more source

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