Results 31 to 40 of about 504,503 (314)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Solution of nonlinear Volterra integral equations with a locally loaded operator

Известия высших учебных заведений. Поволжский регион: Физико-математические науки
Background. The study is devoted to the construction of a numerical solution of nonlinear integral equations containing a local load. Such equations are used in the modeling of dynamic systems, and a number of boundary value problems, in particular, the ...
Danila R. Vechkasov, Aleksandr N. Tynda
doaj   +1 more source

On the Morávek and Vlach conditions for the existence of a solution to the multi-index problem [PDF]

, 1975
summary:The smallest prossible example of a 3 index multi-index problem which satisfies the 1967 Morávek and Vlach conditions but does not have a solution is ...
Smith, Graham
core   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Existence of a positive solution for a p-Laplacian semipositone problem

Boundary Value Problems, 2005
We consider the boundary value problem −Δpu=λf(u) in Ω satisfying u=0 on ∂Ω, where u=0 on ∂Ω, λ>0 is a parameter, Ω is a bounded domain in ℝn with C2 boundary ∂Ω, and Δpu:=div(|∇u|p−2∇u ...
R. Shivaji, Maya Chhetri
doaj   +1 more source

The determination of necessary and sufficient conditions for the existence of a solution to the $3\times3\times3$ multi-index problem

, 1979
summary:Modifications to a procedure for determining necessary and sufficient conditions for the existence of a solution to the multi-index problem are described.
Smith, Graham, Dawson, Jeremy
core   +1 more source

Numerical solution of the Falkner-Skan equation using third-order and high-order-compact finite difference schemes [PDF]

, 2011
We present a computational study of the solution of the Falkner-Skan equation (a third-order boundary value problem arising in boundary-layer theory) using high-order and high-order-compact finite differences schemes.
Galeano, Carlos, Duque-Daza, Carlos, Duque-Daza,Carlos, Lockerby,Duncan, Lockerby, Duncan A., Galeano,Carlos   +5 more
core   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

Existence of viscosity solution for a singular Hamilton–Jacobi equation

Arab Journal of Mathematical Sciences, 2015
In this paper we study the existence of a singular Hamilton–Jacobi equation under the framework of viscosity solutions. The analysis is inspired by the arguments of [8] where a study of a model on dislocation dynamics was considered.
H. Ibrahim, S. Zabad
doaj   +1 more source