Results 101 to 110 of about 310,792 (316)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Multiple boundary peak solutions for some singularly perturbed Neumann problems [PDF]

open access: yes, 2000
We consider the problem \left \{ \begin{array}{rcl} \varepsilon^2 \Delta u - u + f(u) = 0 & \mbox{ in }& \ \Omega\\ u > 0 \ \mbox{ in} \ \Omega, \ \frac{\partial u}{\partial \nu} = 0 & \mbox{ on }& \ \partial\Omega, \end{array} \right. where \
Gui, Changfeng   +8 more
core   +1 more source

Existence of solutions for Hardy-Sobolev-Maz'ya systems

open access: yesElectronic Journal of Differential Equations, 2012
The main goal of this article is to investigate the existence of solutions for the Hardy-Sobolev-Maz'ya system $$displaylines{ -Delta u-lambda frac{u}{|y|^2}=frac{|v|^{p_t-1}}{|y|^t}v,quad hbox{in }Omega,cr -Delta v-lambda frac{v}{|y|^2}=frac{|u ...
Jian Wang, Xin Wei
doaj  

Existence of Solutions for Linear Moment Problems [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2007
The Cimmino algorithm is an iterative projection method for finding almost common points of measur- able families of closed convex sets in a Hilbert space.
Dan Butnariu, Benzion Shklyar
doaj  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Meinong and Husserl on Existence. Two Solutions of the Paradox of Non-Existence

open access: yesPhilosophia Scientiæ, 2014
This paper analyzes and compares the attempts at solving the paradox of non-existence put forward by Alexius Meinong and Edmund Husserl. It will be argued that Meinong's solution is not convincing since he retreats from the field of predicate logic, in ...
Giuliano Bacigalupo
doaj   +1 more source

A Technique for Proving Existence of Solutions

open access: yesJournal of Mathematical Analysis and Applications, 1997
Problems of the form \[ x'(t)= f(t,x(t)),\qquad t\in[0,T], \quad x(0)\neq x_0,\tag{IVP} \] where \(T\in \mathbb{R}^+\), \(x_0\in \mathbb{R}^N\), and \(f:\mathbb{R}\times \mathbb{R}^N\to \mathbb{R}^N\) are considered and the existence of Carathéodory solutions of (IVP) is studied.
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Positive solutions of a boundary value problem with integral boundary conditions [PDF]

open access: yes, 2011
We consider boundary-value problems studied in a recent paper. We show that some existing theory developed by Webb and Infante applies to this problem and we use the known theory to show how to find improved estimates on parameters μ*, λ so ...
Webb, J.
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

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