Results 131 to 140 of about 310,792 (316)

Existence of solutions for second-order evolution inclusions

open access: yes, 1993
In this paper we examine second-order nonlinear evolution inclusions and prove two existence theorems; one with a convex-valued orientor field and the other with a nonconvex-valued field. An example of a hyperbolic partial differen-tial inclusion is also
Papageorgiou, N   +2 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Existence, classification and stability analysis of multiple-peaked solutions for the gierer-meinhardt system in R^1

open access: yes, 2007
We consider the Gierer-Meinhardt system in R^1. where the exponents (p, q, r, s) satisfy 1< \frac{ qr}{(s+1)( p-1)} < \infty, 1
Winter, M, Wei, J
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Existence and non-existence of solutions for a p(x)-biharmonic problem

open access: yesElectronic Journal of Differential Equations, 2015
In this article, we study the following problem with Navier boundary conditions $$\displaylines{ \Delta (|\Delta u|^{p(x)-2}\Delta u)+|u|^{p(x)-2}u =\lambda |u|^{q(x)-2}u +\mu|u|^{\gamma(x)-2}u\quad \text{in } \Omega,\cr u=\Delta u=0 \quad \text{on
Ghasem A. Afrouzi   +2 more
doaj  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Existence of solutions for iterative differential equations

open access: yesElectronic Journal of Differential Equations, 2014
The presence of self-mapping increases the difficulty in proving the existence of solutions for general iterative differential equation. In this article we provide conditions for the existence of solutions for the initial value problem, in which the ...
Pingping Zhang, Xiaobing Gong
doaj  

EXISTENCE AND UNIQUENESS OF CHAIN LADDER SOLUTIONS

open access: yesASTIN Bulletin, 2015
AbstractThe cross-classified chain ladder has a number of versions, depending on the distribution to which observations are subject. The simplest case is that of Poisson distributed observations, and then maximum likelihood estimates of parameters are explicit.
openaire   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Existence of solutions for fractional Hamiltonian systems

open access: yesElectronic Journal of Differential Equations, 2013
In this work we prove the existence of solutions for the fractional differential equation $$ _{t}D_{\infty}^{\alpha}(_{-\infty}D_{t}^{\alpha}u(t)) + L(t)u(t) = \nabla W(t,u(t)),\quad u\in H^{\alpha}(\mathbb{R}, \mathbb{R}^{N}). $$ where $\alpha
Cesar Torres
doaj  

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