Results 141 to 150 of about 310,792 (316)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Coagulation and fragmentation processes with evolving size and shape profiles : a semigroup approach
, 2013 We investigate a class of bivariate coagulation-fragmentation equations. These equations describe the evolution of a system of particles that are characterised not only by a discrete size variable but also by a shape variable which can be either discrete
Smith, Ann Louise +2 more
core +1 more source
Existence of positive solutions for Kirchhoff problems
Electronic Journal of Differential Equations, 2015 We study problems for the Kirchhoff equation $$\displaylines{ -\Big(a+b\int_{\Omega}|\nabla u|^2dx\Big)\Delta u =\nu u^3+ Q(x)u^{q},\quad \text{in }\Omega, \cr u=0, \quad \text{on }\partial\Omega, }$$ where $\Omega\subset \mathbb{R}^3$ is a ...
Jia-Feng Liao, Peng Zhang, Xing-Ping Wu
doaj
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Existence of travelling wave solutions for a model of tumour invasion
, 2014 The existence of travelling wave solutions to a haptotaxis dominated model is analysed. A version of this model has been derived in Perumpanani et al. (1999) to describe tumour invasion, where diffusion is neglected as it is assumed to play only a small ...
Wechselberger, M. +4 more
core +1 more source
Existence of solutions for Kirchhoff type equations
Electronic Journal of Differential Equations, 2015 In this article, we prove the existence of solutions for Kirchhoff type equations with Dirichlet boundary-value condition. We use the Mountain Pass Theorem in critical point theory, without the (PS) condition.
Qi-Lin Xie, Xing-Ping Wu, Chun-Lei Tang
doaj
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Optimal control of stochastic partial differential equations in Banach spaces [PDF]
, 2010 In this thesis we study optimal control problems in Banach spaces for stochastic partial differential equations. We investigate two different approaches.
Serrano Perdomo, Rafael Antonio +1 more
core
Existence of solutions for thermoelastic semiconductor equations
Electronic Journal of Differential Equations, 2009 We study a model for the semiconductor problem that consists of a system of dynamic thermoelasticity equations of displacement and semiconductor equations.
Xiaoqin Wu
doaj