Results 101 to 110 of about 216,543 (287)

Effect of Nozzle Contour on Flow Separation in Overexpanded Rocket Nozzles

Journal of Fluid Science and Technology, 2007
In the present paper, parametric numerical analyses of the separated transonic flows in overexpanded rocket nozzles are conducted. Several types of nozzles are examined numerically to clarify the detailed mechanisms of the occurrence of restricted shock ...
Koichi YONEZAWA, Yukinori YAMASHITA, Yoshinobu TSUJIMOTO, Yasuhide WATANABE, Kazuhiko YOKOTA   +4 more
doaj   +1 more source

Heterogeneity, State Dependence and Health [PDF]

We investigate the evolution of health over the life-cycle. We allow for two sources of persistence: unobserved heterogeneity and state dependence. Estimation indicates that there is a large degree of heterogeneity.
Halliday, Timothy
core  

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Exit without choice: interpretable machine learning unlocks the structural drivers of smallholder dispossession in Pakistan

Agricultural and Food Economics
In Pakistan’s evolving agricultural landscape, smallholder farmers are increasingly exiting farming, not by choice but under structural pressure. This study investigates the underlying associations using an integrated machine learning and econometric ...
Ghazi Abbas, Zhou Ying, Chi Goutai, Qamar Abbas, Khalil El Hindi   +4 more
doaj   +1 more source

An investigation of corner separation within a thrust augmenter having Coanda jets [PDF]

, 1979
The development of separation in corners of thrust augmentor wings having Coanda jets was investigated using hot film surface sensors and pressure transducers.
Seiler, M. R.
core   +1 more source

Interaction of Wnt and SHH gradients synchronizes cell cycle exit and differentiation

Summary How signals coordinate cellular proliferation with differentiation to regulate cell fate transitions is poorly understood. Hair follicle dermal condensates (DCs) emerge in developing skin from an acute cell fate transition in which cell cycle exit and molecular differentiation occur simultaneously.
Li, Ruiqi, Jiang, Yiqun, Platt, Sarah, Peterson, Kevin A., Lam, Hainan, Van, Sarah, Lim, Chae Ho, Levinsohn, Jonathan, Barber, Eva-Larue, Wang, David, Taketo, M. Mark, Kluger, Yuval, Myung, Peggy   +12 more
openaire   +1 more source

Explainable machine learning surrogate modeling for exit gradient prediction in hydraulic structures using numerical simulations

Journal of Hydroinformatics
ABSTRACT Accurate prediction of exit gradients is essential for designing impounding hydraulic structures, such as dams and levees, to mitigate seepage-induced piping failures. Conventional analytical methods often neglect boundary effects and anisotropy, limiting their applicability in complex geological settings.
Prayas Rath, Jianting Zhu, Kevin M. Befus   +2 more
openaire   +1 more source

The Spatial–Temporal Gradient of Naturally Occurring Motoneuron Death Reflects the Time of Prior Exit from the Cell Cycle and Position within the Lateral Motor Column

Developmental Biology, 1999
Embryonic lumbar spinal motoneurons (MNs) are characterized by a period of programmed cell death (PCD) that spans several days and occurs in a rostrocaudal gradient. The generation of these MNs also takes place in a temporal-spatial gradient, such that MNs within rostral lumbar segments exit the cell cycle earlier and MNs within progressively caudal ...
Gould, Thomas W., Burek, Michael J., Sosnowski, Jennifer M., Prevette, David, Oppenheim, Ronald W.   +4 more
openaire   +2 more sources

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Controlling Seepage Flow Beneath Hydraulic Structures: Effects of Floor Openings and Sheet Pile Wall Cracks

Buildings
Using one opening (filter) within the floors of hydraulic structures is a known technique to relieve the seepage effects on their floors. In this study, a new method to control seepage flow by using two identical filters instead of one was tackled ...
Mohamed Farouk
doaj   +1 more source