Results 41 to 50 of about 216,543 (287)

Seepage Quantity Analysis Beneath Concrete Dams with Various Sheet Piles using Different Numerical Models

open access: yesTikrit Journal of Engineering Sciences, 2023
Seepage is a dangerous phenomenon under hydraulic structures and the main cause of failure and damage to dams when neglected and not processed. This study evaluates the numerical effects of the sheet piles' quantity, depth, and spacing beneath a ...
Taban K. Hamad   +2 more
doaj   +1 more source

On the fast convergence of random perturbations of the gradient flow

open access: yes, 2020
We consider in this work small random perturbations (of multiplicative noise type) of the gradient flow. We prove that under mild conditions, when the potential function is a Morse function with additional strong saddle condition, the perturbed gradient ...
Hu, Wenqing   +2 more
core   +1 more source

Coherent Transport of Angular Momentum - The Ranque-Hilsch Tube as a Paradigm [PDF]

open access: yes, 1999
The mechanism for efficient and coherent angular momentum transport remains one of the unsolved puzzles in astrophysics despite the enormous efforts that have been made.
Abramowicz   +15 more
core   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Scaling laws of passive tracer dispersion in the turbulent surface layer

open access: yes, 2010
Experimental results for passive tracer dispersion in the turbulent surface layer under stable conditions are presented. In this case, the dispersion of tracer particles is determined by the interplay of three mechanisms: relative dispersion (celebrated ...
DuBois, Timothy C.   +2 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Analytical Solution for the Steady Seepage Field of a Foundation Pit in an Anisotropic Layer

open access: yesBuildings
The soil piping and drift sand phenomenon is one of the catastrophic failure forms in foundation pit excavations in coastal buildings. Presently, there is a deficiency in the theoretical research regarding the seepage fields around foundation pits ...
Yulin Zeng   +3 more
doaj   +1 more source

Branching diffusion representation of semi-linear elliptic PDEs and estimation using Monte Carlo method [PDF]

open access: yes, 2018
We study semi-linear elliptic PDEs with polynomial non-linearity and provide a probabilistic representation of their solution using branching diffusion processes.
Agarwal, Ankush, Claisse, Julien
core   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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