Results 151 to 160 of about 838,049 (387)

Lipopolysaccharide Purified from Salmonella typhi Sensitizes Human Red Blood Cells at Hemagglutinin concentration, leading to complete Hemolysis upon the addition of Jacalin- a lectin from Jackfruit

Exon
Lipopolysaccharides consist of a hydrophilic-polysaccharide region and a hydrophobic lipid compound known as lipid A. LPS has been reported to cause concentration-dependent agglutination of human RBCs. In this study, the HAP-Hot Aqueous-Phenol Extraction
Logesh Radhakrishnan, V Lavanya, Shazia Jamal, Neesar Ahmed   +3 more
doaj   +1 more source

End‐to‐End Sensing Systems for Breast Cancer: From Wearables for Early Detection to Lab‐Based Diagnosis Chips

Advanced Materials Technologies, EarlyView.
This review explores advances in wearable and lab‐on‐chip technologies for breast cancer detection. Covering tactile, thermal, ultrasound, microwave, electrical impedance tomography, electrochemical, microelectromechanical, and optical systems, it highlights innovations in flexible electronics, nanomaterials, and machine learning.
Neshika Wijewardhane, Lyn I. Jones, Richard M. Martin, Helen Winter, Faezeh Arab Hassani   +4 more
wiley   +1 more source

Implementing One Health approach to emerging zoonotic diseases: Bridging surveillance, sustainability and global governance

Exon
The One Health approach offers a pragmatic and policy-relevant framework that integrates human, animal, and environmental health systems to confront the rising threat of zoonotic diseases.
Kingsley Excel Dunga, Chinyere Ihuarulam Okoro, Amarachi Chisom Onyenama, Uchechukwu Onyeukwu Ekuma, Irene Nneka Ohanusi, Sylvester Chibueze Izah   +5 more
doaj   +1 more source

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source

Polymer-Based Nanoparticles as Efficient Non-Viral Vectors for Gene Delivery in CAR-T Cell Therapy

Exon
Chimeric Antigen Receptor (CAR)-T cell therapy has emerged as a revolutionary method in cancer immunotherapy, achieving notable success in treating hematological malignancies.
Debtosh Patra
doaj   +1 more source

Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice

Cell, 1996
L. Mangiarini, K. Sathasivam, M. Seller, Barbara A. Cozens, Alex J. Harper, C. Hetherington, Martin Lawton, Y. Trottier, H. Lehrach, S. Davies, G. Bates   +10 more
semanticscholar   +1 more source

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

Advanced Science, EarlyView.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu, Jing Luo, Li Yu, Daoxi Qi, Boyu Li, Yating Chen, Chen Wang, Xiaokang Zhang, Wenzheng Guo, Qiyong Lou, Gang Zhai, Yonglin Ruan, Jianfei Huang, Shengchi Shi, Zhan Yin, Fang Zheng   +15 more
wiley   +1 more source

Preliminary In Silico Evaluation of Potential Therapeutics for Non-Alcoholic Steatohepatitis (NASH) using Molecular Docking and Pharmacokinetics Analysis

Exon
Non‑alcoholic steatohepatitis (NASH) is a progressive inflammatory liver disease arising from non‑alcoholic fatty liver disease (NAFLD) and is increasingly prevalent due to rising obesity, insulin resistance, and sedentary lifestyle.
Sudarsna B, Gokulkrishnan A
doaj   +1 more source

Investigation into the relationship between ethylene and sulfur assimilation in Arabidopsis thaliana and onion (Allium cepa L.) : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science (with Honours) in Biochemistry at Massey University [PDF]

, 2006
The phytohormone ethylene (C2H4) mediates the adaptive responses of plants to various nutrient deficiencies including iron (Fe)-deficiency, phosphorus (P)-deficiency and potassium (K)-deficiency.
Sanggang, Fiona Ann
core  

Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS

Advanced Science, EarlyView.
This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu, Hongzhi Li, Xiang Li, Chunxiu Du, Ting Wang, Xuling Zhou, Xiaobei Xie, Yunxia Shao, Yingzhi Huang, Yanling Hu, Xinxin Guo, Bin Zhu, Shanshan Yu, Xiaoyan Zhang, Binghai Zhao   +14 more
wiley   +1 more source