Results 11 to 20 of about 19,628 (74)

Inhomogeneous DNA: conducting exons and insulating introns [PDF]

Phys. Rev. B 80 (2009) 085420, 2009
Parts of DNA sequences known as exons and introns play very different role in coding and storage of genetic information. Here we show that their conducting properties are also very different. Taking into account long-range correlations among four basic nucleotides that form double-stranded DNA sequence, we calculate electron localization length for ...
arxiv   +1 more source

Universal power law behaviors in genomic sequences and evolutionary models [PDF]

, 2007
We study the length distribution of a particular class of DNA sequences known as 5'UTR exons. These exons belong to the messanger RNA of protein coding genes, but they are not coding (they are located upstream of the coding portion of the mRNA) and are thus less constrained from an evolutionary point of view.
arxiv   +1 more source

The Alternative Choice of Constitutive Exons throughout Evolution [PDF]

PLoS Genet 2007 3(11): e203, 2008
Alternative cassette exons are known to originate from two processes exonization of intronic sequences and exon shuffling. Herein, we suggest an additional mechanism by which constitutively spliced exons become alternative cassette exons during evolution. We compiled a dataset of orthologous exons from human and mouse that are constitutively spliced in
arxiv  

The relationships among GC content, nucleosome occupancy, and exon size [PDF]

arXiv, 2014
The average size of internal translated exons, ranging from 120 to 165 nt across metazoans, is approximately the size of the typical mononucleosome (147 nt). Genome-wide study has also shown that nucleosome occupancy is significantly higher in exons than in introns, which might indicate that the evolution of exon size is related to its nucleosome ...
arxiv  

A Machine Learning Strategy to Identity Exonic Splice Enhancers in Human Protein-coding Sequence [PDF]

arXiv, 2004
Background: Exonic splice enhancers are sequences embedded within exons which promote and regulate the splicing of the transcript in which they are located. A class of exonic splice enhancers are the SR proteins, which are thought to mediate interactions between splicing factors bound to the 5' and 3' splice sites.
arxiv  

A Gene Prediction Method Based on Statistics and Signal Processing [PDF]

arXiv, 2014
Bioinformatics, as an emerging and rapidly developing interdisciplinary, has become a promising and popular research field in 21st century. Extracting and explaining useful biological information from huge amount of genetic data is an urgent issue in post-genome era. In eukaryotic DNA sequences, gene consists of exons and introns.
arxiv  

Intronic Alus Influence Alternative Splicing [PDF]

PLoS Genet 2008 4(9): e1000204, 2008
Examination of the human transcriptome reveals higher levels of RNA editing than in any other organism tested to date. This is indicative of extensive double-stranded RNA (dsRNA) formation within the human transcriptome. Most of the editing sites are located in the primate-specific retrotransposed element called Alu.
arxiv  

SASeq: A Selective and Adaptive Shrinkage Approach to Detect and Quantify Active Transcripts using RNA-Seq [PDF]

arXiv, 2012
Identification and quantification of condition-specific transcripts using RNA-Seq is vital in transcriptomics research. While initial efforts using mathematical or statistical modeling of read counts or per-base exonic signal have been successful, they may suffer from model overfitting since not all the reference transcripts in a database are expressed
arxiv  

HOW TO USE EXON RESINS PLUS Firestone TECHNICAL SERVICE ...for a shortcut to a better [PDF]

, 1953

openalex   +1 more source

Faster exon assembly by sparse spliced alignment [PDF]

arXiv, 2007
Assembling a gene from candidate exons is an important problem in computational biology. Among the most successful approaches to this problem is \emph{spliced alignment}, proposed by Gelfand et al., which scores different candidate exon chains within a DNA sequence of length $m$ by comparing them to a known related gene sequence of length n, $m ...
arxiv