Results 11 to 20 of about 394,574 (252)
Frontiers in Neurology, 2020 Genome-wide association studies have identified putative ischemic stroke risk genes, yet, their expression after stroke is unexplored in spite of growing interest in elucidating their specific role and identifying candidate genes for stroke treatment ...
Cheryl Dykstra-Aiello +11 more
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Prevalent use and evolution of exonic regulatory sequences in the human genome
Natural Sciences, 2023 It has long been known that exons can serve as cis‐regulatory sequences, such as enhancers. However, the prevalence of such dual‐use of exons and how they evolve remain elusive.
Jing Chen +5 more
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A Bidirectional LSTM-RNN and GRU Method to Exon Prediction Using Splice-Site Mapping
Applied Sciences, 2022 Deep Learning techniques (DL) significantly improved the accuracy of predictions and classifications of deoxyribonucleic acid (DNA). On the other hand, identifying and predicting splice sites in eukaryotes is difficult due to many erroneous discoveries ...
Peren Jerfi CANATALAY, Osman Nuri Ucan
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Cell, 1991 Using a sensitive assay for RNA expression, we identified several abnormally spliced transcripts in which exons from a candidate tumor suppressor gene (DCC) were scrambled during the splicing process in vivo. Cloning and sequencing of PCR-amplified segments of the abnormally spliced transcripts showed that exons were joined accurately at consensus ...
J M, Nigro +7 more
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Frequencies of the MEFV Gene Mutations in Azerbaijan
Balkan Journal of Medical Genetics, 2022 The MEFV (familial Mediterranean fever gene) researches were performed in the population of the Republic of Azerbaijan in 2016–2021. Seven mutations of the MEFV gene were identified in heterozygous, homozygous and compound homozygous conditions: R761H ...
Huseynova LS, Mammadova SN, Aliyeva KAA
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Identification of a dinucleotide signature that discriminates coding from non-coding long RNAs
Frontiers in Genetics, 2014 To date, the main criterion by which long ncRNAs (lncRNAs) are discriminated from mRNAs is based on the capacity of the transcripts to encode a protein. However, it becomes important to identify non-ORF-based sequence characteristics that can be used to ...
Damien eUlveling +3 more
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Exon Skipping Is Correlated with Exon Circularization
Journal of Molecular Biology, 2015 Circular RNAs are found in a wide range of organisms and it has been proposed that they perform disparate functions. However, how RNA circularization is connected to alternative splicing remains largely unexplored. Here, we stimulated primary human endothelial cells with tumor necrosis factor α or tumor growth factor β, purified RNA, generated >2.4 ...
Kelly, S +3 more
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Veterinary Sciences, 2020 DNA methylation of different gene components, including different exons and introns, or different lengths of exons and introns is associated with differences in gene expression.
Xiao Wang, Haja N. Kadarmideen
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Life, 2016 The abundance of mammalian long intergenic non-coding RNA (lincRNA) genes is high, yet their functions remain largely unknown. One possible way to study this important question is to use large-scale comparisons of various characteristics of lincRNA with ...
Diana Chernikova +4 more
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From Order to Chaos: Publication, Synthesis and the Dissemination of Data in a Digital Age
Internet Archaeology, 1999 In the past, the provision of authoritative, interpretative, syntheses is what archaeologists sought through publication. Now the first real challenge of the digital age has been to balance this trend and in contrast to archaeological practice over the ...
Vince Gaffney , Sally Exon
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