Results 331 to 340 of about 667,667 (355)
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The ribosome as an exon detector
Biosystems, 1996We present an analysis where different regions of small subunit rRNA are tested for their capacity to discriminate between coding and non-coding regions. We find that the 530 loop is one of the best sequences to be used in an algorithm for detecting exonic sites.
Jaime Lagúnez-Otero, Luis Mendoza
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Current Opinion in Structural Biology, 1994
Abstract Analysis of the exon-intron structures of genes, and a survey of the evolutionary distribution of mosaic proteins suggest that modularization of protein domains by intron insertions and their dispersal through exon-shuffling become significant only in higher eukaryotes.
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Abstract Analysis of the exon-intron structures of genes, and a survey of the evolutionary distribution of mosaic proteins suggest that modularization of protein domains by intron insertions and their dispersal through exon-shuffling become significant only in higher eukaryotes.
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Skipping of multiple CFTR exons is not a result of single exon omissions
Human Genetics, 1994The omission of complete exons in a proportion of mature transcripts has been shown for a variety of genes. In the case of the cystic fibrosis transmembrane conductance regulator gene, this phenomenon has previously been observed for exons 4, 9 and 12.
Jochen Reiss +3 more
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Science, 1999
Retrotransposons are mobile elements that move through the genome by reverse transcription of their RNA template. In his Perspective, Tom Eickbush discusses new findings reported in this issue by [Moran and colleagues][1] that suggest that the insertion of retrotransposable elements in the genome can be beneficial rather than deleterious as previously ...
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Retrotransposons are mobile elements that move through the genome by reverse transcription of their RNA template. In his Perspective, Tom Eickbush discusses new findings reported in this issue by [Moran and colleagues][1] that suggest that the insertion of retrotransposable elements in the genome can be beneficial rather than deleterious as previously ...
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EGFR and HER2 exon 20 insertions in solid tumours: from biology to treatment
Nature Reviews Clinical Oncology, 2021Alex Friedlaender +2 more
exaly
TDP-43 represses cryptic exon inclusion in the FTD–ALS gene UNC13A
Nature, 2022X Rosa, Mercedes Prudencio, Yuka Koike
exaly
Antitumor activity of crizotinib in lung cancers harboring a MET exon 14 alteration
Nature Medicine, 2020Alexander Drilon +2 more
exaly
Single-nuclei isoform RNA sequencing unlocks barcoded exon connectivity in frozen brain tissue
Nature Biotechnology, 2022Wen Hu, Anoushka Joglekar, Li Fan
exaly