Results 11 to 20 of about 260,440 (253)
Molecular Cell, 2010 Pathways of intron/exon specification that drive spliceosome assembly remain unclear. In this issue of Molecular Cell, Schneider et al. (2010) extensively characterize complexes formed on exons, demonstrating unexpected components and providing insights into the switch from cross-exon to cross-intron interactions.
Moldón, Alberto, Query, Charles
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Plants, 2020 Palms are conspicuous floristic elements across the tropics. In continental Africa, even though there are less than 70 documented species, they are omnipresent across the tropical landscape.
Andrew J. Helmstetter +10 more
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Detection of internal exon deletion with exon Del [PDF]
BMC Bioinformatics, 2014 Exome sequencing allows researchers to study the human genome in unprecedented detail. Among the many types of variants detectable through exome sequencing, one of the most over looked types of mutation is internal deletion of exons. Internal exon deletions are the absence of consecutive exons in a gene.
Yan Guo +7 more
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ExPrimer: to design primers from exon--exon junctions [PDF]
Bioinformatics, 2005 ExPrimer is a web-based computer program to design primers mainly from a specified exon-exon junction (E-E-jn) of a gene of interest. The tool suggests the optimum primer-pair(s) of which the right (reverse) primer represents a particular E-E-jn of the mRNA. The 'product length' decides the location of the left primer.
Kuljeet S. Sandhu, Kshitish K. Acharya
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Frontiers in Marine Science, 2021 The octocoral genus Chrysogorgia (Duchassaing and Michelotti, 1864) contains 81 nominal species that are ecologically important components of benthic communities.
Candice Bobby Untiedt +8 more
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Evolutionary perspective of Big tau structure: 4a exon variants of MAPT
Frontiers in Molecular Neuroscience, 2022 The MAPT gene encoding the microtubule-associated protein tau can generate multiple isoforms by alternative splicing giving rise to proteins which are differentially expressed in specific areas of the nervous system and at different developmental stages.
Itzhak Fischer
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Exon Skipping Is Correlated with Exon Circularization
Journal of Molecular Biology, 2015 Circular RNAs are found in a wide range of organisms and it has been proposed that they perform disparate functions. However, how RNA circularization is connected to alternative splicing remains largely unexplored. Here, we stimulated primary human endothelial cells with tumor necrosis factor α or tumor growth factor β, purified RNA, generated >2.4 ...
Kelly, S +3 more
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In Vivo Recognition of a Vertebrate Mini-Exon as an Exon-Intron-Exon Unit
Molecular and Cellular Biology, 1993 Very small vertebrate exons are problematic for RNA splicing because of the proximity of their 3' and 5' splice sites. In this study, we investigated the recognition of a constitutive 7-nucleotide mini-exon from the troponin I gene that resides quite close to the adjacent upstream exon.
D A, Sterner, S M, Berget
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Identify alternative splicing events based on position-specific evolutionary conservation. [PDF]
PLoS ONE, 2008 The evolution of eukaryotes is accompanied by the increased complexity of alternative splicing which greatly expands genome information. One of the greatest challenges in the post-genome era is a complete revelation of human transcriptome with ...
Liang Chen, Sika Zheng
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Cell, 1991 Using a sensitive assay for RNA expression, we identified several abnormally spliced transcripts in which exons from a candidate tumor suppressor gene (DCC) were scrambled during the splicing process in vivo. Cloning and sequencing of PCR-amplified segments of the abnormally spliced transcripts showed that exons were joined accurately at consensus ...
J M, Nigro +7 more
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