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Characterization of exoribonuclease XRN1 as a cancer target and identification of adenosine-3',5'-bisphosphate as a potent enzyme inhibitor. [PDF]

open access: yesCommun Biol
Lockbaum GJ   +21 more
europepmc   +1 more source
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Drosophila 5′ → 3′-Exoribonuclease Pacman

Methods in enzymology, 2001
Publisher Summary This chapter concentrates on the methods used to express a Drosophila recombinat 5′ → 3′-exoribonuclease, purify the protein, and analyze its activity in vitro . Analysis of early development in Drosophila has shown that RNA localization, control of translation, and mRNA stability are intimately linked.
I V, Chernukhin   +2 more
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