Results 261 to 270 of about 14,025 (272)

Structures and exoribonuclease activity fonctions in arenavirus and coronavirus.

Virologie (Montrouge, France), 2013
RNA viruses encode dedicated protein machinery required through the viral life cycle. Some enzymatic activities are generally associated with RNA viruses such as RNA- or DNA-dependent RNA polymerases, RNA helicases or proteases. Some viral enzyme activities are however unique to some viral families.
Isabelle Imbert, François Ferron, Etienne Decroly, Bruno Canard, Mickaël Bouvet   +4 more
openaire   +3 more sources

Single-base resolution mapping of 2′-O-methylation sites by an exoribonuclease-enriched chemical method

Science China Life Sciences, 2022
Ping Zhang, Junhong Huang, Wu-Jian Zheng, Lifan Chen, Shurong Liu, Anrui Liu, Jiayi Ye, Jie Zhou, Zhi-Rong Chen, Qiaojuan Huang, Shun Liu, Ke-ren Zhou, Lianghu Qu, Bin Li, Jianhua Yang   +14 more
semanticscholar   +1 more source

5′ → 3′-Exoribonuclease from Rabbit Reticulocytes

2001
Publisher Summary It has been demonstrated that 5′ → 3′-ribonucleases play an important role in the decay of mRNAs in yeast cells. A 5′ → 3′-ribonuclease from yeast cells named Xrn1p has been purified and cloned. Other 5′ → 3′-exoribonucleases have been partially purified from nuclei of mammalian cells.
openaire   +3 more sources

Chapter 5 The Role of 3′–5′ Exoribonucleases in RNA Degradation

2009
RNA degradation is a major process controlling RNA levels and plays a central role in cell metabolism. From the labile messenger RNA to the more stable noncoding RNAs (mostly rRNA and tRNA, but also the expanding class of small regulatory RNAs) all molecules are eventually degraded.
Cecília M. Arraiano, Vânia Pobre, Susana Domingues, José M. Andrade, Inês J. Silva   +4 more
openaire   +3 more sources

The PPR domain of mitochondrial RNA polymerase is an exoribonuclease required for mtDNA replication in Drosophila melanogaster

Nature Cell Biology, 2022
Y. Liu, Zhe Chen, Zong-Heng Wang, Katherine M. Delaney, Juanjie Tang, M. Pirooznia, Duck‐Yeon Lee, I. Tunc, Yuesheng Li, Hong Xu   +9 more
semanticscholar   +1 more source

Structure and Degradation Mechanisms of 3′ to 5′ Exoribonucleases

2011
Exoribonucleases are enzymes that cleave RNA molecules by removing terminal nucleotides from the 3′ or 5′ end of the RNA molecules. They are key factors in RNA metabolism and have a relevant role in the processing and degradation of all types of RNAs.
José M. Andrade, Filipa P. Reis, Cecília M. Arraiano, Michal Malecki, Vânia Pobre, Rute G. Matos   +5 more
openaire   +2 more sources

XRN1: A Major 5′ to 3′ Exoribonuclease in Eukaryotic Cells

2012
The degradation of RNA is a critical aspect of gene regulation. Correspondingly, ribonucleases exist within the cell to degrade RNA in specific cellular contexts. An important and conserved ribonuclease is called XRN1. This enzyme, an exoribonuclease, degrades RNA in a processive 5' to 3' direction.
Sarah Geisler, Jeff Coller
openaire   +3 more sources

Structural basis of exoribonuclease-mediated mRNA transcription termination.

Nature
Yuan Zeng, Hongwei Zhang, Xiaoxian Wu, Yu Zhang   +3 more
semanticscholar   +1 more source

RNase R vs. PNPase: selecting the best-suited exoribonuclease for environmental adaptation.

Extremophiles
T. Pavankumar
semanticscholar   +1 more source

Lactobacillus plantarum exoribonuclease. Further purification and characterization

Biochemistry, 1971
David M. Logan, Enore C. Gardonio
openaire   +3 more sources