Results 121 to 130 of about 182,132 (342)

Unraveling the Heterogeneity of Cargo Distribution in the Exogenous Association of Proteins With Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, EarlyView.
We characterized the distribution of cargo proteins associated with extracellular vesicles using various exogenous loading methods. In all cases, single‐particle analysis revealed that the distribution of protein content per EV is heterogeneous, following an exponential decay function.
Karl Normak   +6 more
wiley   +1 more source

Exosomal lipid composition and the role of ether lipids and phosphoinositides in exosome biology

open access: yesJournal of Lipid Research, 2018
Exosomes are a type of extracellular vesicle released from cells after fusion of multivesicular bodies with the plasma membrane. These vesicles are often enriched in cholesterol, SM, glycosphingolipids, and phosphatidylserine.
T. Skotland   +3 more
semanticscholar   +1 more source

Exosome biogenesis, secretion and function of exosomal miRNAs in skeletal muscle myogenesis

open access: yesCell Proliferation, 2020
Exosomes are membrane‐bound extracellular vesicles that are produced in the endosomal compartment of most mammalian cell types and then released. Exosomes are effective carriers for the intercellular material transfer of material that can influence a ...
Binglin Yue   +8 more
semanticscholar   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

open access: yesAdvanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee   +9 more
wiley   +1 more source

Extracellular vesicle isolation and counting system (EVics) based on simultaneous tandem tangential flow filtration and large field‐of‐view light scattering

open access: yesJournal of Extracellular Vesicles
Although the isolation and counting of small extracellular vesicles (sEVs) are essential steps in sEV research, an integrated method with scalability and efficiency has not been developed.
Ju‐Hyun Bae   +6 more
doaj   +1 more source

Lysosomal Delivery of Bioactive Proteins to Living Human Cells via Engineered Exosomes [PDF]

open access: yes, 2018
Exosomes are naturally secreted nanovesicles derived from mammalian cells that are used for intercellular communication in vivo. As a result, they can potentially be used for intracellular delivery of therapeutics for disease treatment. We have developed
Levy, Daniel
core   +1 more source

Extracellular vesicles, ageing, and therapeutic interventions [PDF]

open access: yes, 2018
A more comprehensive understanding of the human ageing process is required to help mitigate the increasing burden of age-related morbidities in a rapidly growing global demographic of elderly individuals.
Neytchev, Ognian   +3 more
core   +1 more source

BMSC-derived exosomes protect against kidney injury through regulating klotho in 5/6 nephrectomy rats [PDF]

open access: gold, 2022
Feng Wan   +7 more
openalex   +1 more source

Exosome–Liposome Hybrid Nanoparticles Deliver CRISPR/Cas9 System in MSCs

open access: yesAdvancement of science, 2018
Targeted delivery of clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR‐associated protein 9 (Cas9) system to the receptor cells is essential for in vivo gene editing.
Yao Lin   +6 more
semanticscholar   +1 more source

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